EP 3730133 A1 20201028 - FUDOSTEINE SOLUTION PREPARATION FOR AEROSOL INHALATION, AND PREPARATION METHOD THEREFOR
Title (en)
FUDOSTEINE SOLUTION PREPARATION FOR AEROSOL INHALATION, AND PREPARATION METHOD THEREFOR
Title (de)
FUDOSTEINLÖSUNGSPRÄPARAT ZUR INHALATION VON AEROSOL UND VERFAHREN ZU SEINER HERSTELLUNG
Title (fr)
PRÉPARATION DE SOLUTION DE FUDOSTÉINE POUR INHALATION D'AÉROSOL, ET SON PROCÉDÉ DE PRÉPARATION
Publication
Application
Priority
- CN 201711373995 A 20171219
- CN 2018087524 W 20180518
Abstract (en)
Disclosed are a fudosteine solution preparation for aerosol inhalation, and a preparation method therefor. The fudosteine solution preparation for aerosol inhalation comprises fudosteine, salts thereof and/or hydrates thereof; a metal complexing agent; and water for injection. The method for preparing the fudosteine solution preparation for aerosol inhalation includes the following steps: adding water for injection to a liquid formulation device and filling in nitrogen for protection, keeping the nitrogen in a liquid formulation tank at a positive pressure, and determining a residual oxygen content to be less than 2 mg/L; weighing the metal complexing agent, and stirring until the same dissolves; adding fudosteine, salts thereof and/or hydrates thereof, and stirring until the same dissolves; adding a pH adjusting agent, and determining the residual oxygen content to be less than 2 mg/L; supplementing with water for injection to a full amount, and stirring until evenly mixed; and carrying out fine filtration under sterile conditions, encapsulating and filling in nitrogen.
IPC 8 full level
A61K 9/08 (2006.01); A61K 31/198 (2006.01)
CPC (source: EP US)
A61K 9/0073 (2013.01 - EP); A61K 9/0078 (2013.01 - US); A61K 9/08 (2013.01 - EP); A61K 31/198 (2013.01 - EP US); A61K 47/12 (2013.01 - EP US); A61K 47/183 (2013.01 - EP); A61P 11/00 (2017.12 - EP); A61P 11/10 (2017.12 - EP); A61P 11/14 (2017.12 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 3730133 A1 20201028; EP 3730133 A4 20210127; CN 109925300 A 20190625; JP 2021506897 A 20210222; US 2020316003 A1 20201008; WO 2019119720 A1 20190627
DOCDB simple family (application)
EP 18892327 A 20180518; CN 201711373995 A 20171219; CN 2018087524 W 20180518; JP 2020534261 A 20180518; US 202016904117 A 20200617