EP 3752207 A1 20201223 - METHOD FOR PREPARING AN IRRADIATED PLATELET LYSATE
Title (en)
METHOD FOR PREPARING AN IRRADIATED PLATELET LYSATE
Title (de)
VERFAHREN ZUR HERSTELLUNG EINES BESTRAHLTEN BLUTPLÄTTCHENLYSATES
Title (fr)
PROCÉDÉ DE PRÉPARATION D'UN LYSAT PLAQUETTAIRE IRRADIÉ
Publication
Application
Priority
- FR 1851307 A 20180215
- EP 2019053472 W 20190212
Abstract (en)
[origin: WO2019158540A1] The invention relates to a method for preparing an irradiated platelet lysate, comprising the following steps: provision of a starting platelet lysate comprising (i) platelet factors including growth factors and (ii) plasma proteins including coagulation factors and proteins other than the coagulation factors; and double irradiation of the starting platelet lysate, using UVC radiation and ionizing radiation, said double irradiation with UVC radiation and ionizing radiation being arranged to retain at least 75% of the total protein concentration of the starting platelet lysate, while reducing, by at least 40%, the concentration of at least one of the coagulation factors including fibrinogen, factor II, factor VII, factor IX, factor X and factor XI of the starting platelet lysate.
IPC 8 full level
A61L 2/00 (2006.01); C12N 5/078 (2010.01)
CPC (source: EP US)
A61K 41/17 (2020.01 - US); C12N 5/0018 (2013.01 - US); C12N 5/0644 (2013.01 - EP US); C12N 9/6437 (2013.01 - US); C12N 9/644 (2013.01 - US); C12N 9/6443 (2013.01 - US); A61L 2/022 (2013.01 - EP); C12N 2529/00 (2013.01 - EP); C12N 2529/10 (2013.01 - EP US)
Citation (search report)
See references of WO 2019158540A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
FR 3077823 A1 20190816; FR 3077823 B1 20220114; EP 3752207 A1 20201223; US 2021032590 A1 20210204; WO 2019158540 A1 20190822
DOCDB simple family (application)
FR 1851307 A 20180215; EP 19705334 A 20190212; EP 2019053472 W 20190212; US 201916969600 A 20190212