EP 3762038 A1 20210113 - COMPOUNDS FOR MODULATION AND AS FUNCTIONAL REPLACEMENT OF ALPHA-KETOGLUTARIC ACID (2OG)-DEPENDENT OXYGENASES
Title (en)
COMPOUNDS FOR MODULATION AND AS FUNCTIONAL REPLACEMENT OF ALPHA-KETOGLUTARIC ACID (2OG)-DEPENDENT OXYGENASES
Title (de)
VERBINDUNGEN ZUR MODULATION UND ALS FUNKTIONELLER ERSATZ VON ALPHA-KETOGLUTARSÄURE (2OG)-ABHÄNGIGEN OXYGENASEN
Title (fr)
COMPOSÉS POUR LA MODULATION ET LE REMPLACEMENT FONCTIONNEL D'OXYGÉNASES DÉPENDANTES DE L'ACIDE ALPHA-CÉTOGLUTARIQUE (2OG)
Publication
Application
Priority
- LU 100900 A 20180810
- EP 2019071620 W 20190812
Abstract (en)
[origin: WO2020030826A1] The present invention relates to an alternative co-substrate of ketoglutaric acid-dependent dioxygenases for functional production and control of same, with the aim of achieving therapeutic effects against cancer, neurodegenerative diseases and age-related diseases. Epigenetically induced diseases caused by dysregulation and in particular also by metabolic dysfunction in the citric acid cycle are likewise targeted by this therapy.
IPC 8 full level
A61K 47/64 (2017.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01); C12N 9/99 (2006.01)
CPC (source: EP US)
A61K 33/26 (2013.01 - US); A61K 45/06 (2013.01 - US); A61K 47/542 (2017.07 - EP); A61K 47/64 (2017.07 - EP); A61P 35/00 (2017.12 - US); C07F 15/025 (2013.01 - US); C12N 9/0071 (2013.01 - EP); C12Y 114/11 (2013.01 - EP)
Citation (search report)
See references of WO 2020030826A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2020030826 A1 20200213; WO 2020030826 A9 20200409; CN 113164617 A 20210723; EP 3762038 A1 20210113; LU 100900 B1 20200217; US 2021393677 A1 20211223
DOCDB simple family (application)
EP 2019071620 W 20190812; CN 201980066395 A 20190812; EP 19750128 A 20190812; LU 100900 A 20180810; US 201917279331 A 20190812