Global Patent Index - EP 3765854 A1

EP 3765854 A1 20210120 - MARKERS OF SYNAPTOPATHY IN NEURODEGENERATIVE DISEASE

Title (en)

MARKERS OF SYNAPTOPATHY IN NEURODEGENERATIVE DISEASE

Title (de)

MARKER DER SYNAPTOPATHIE BEI NEURODEGENERATIVEN ERKRANKUNGEN

Title (fr)

MARQUEURS DE LA SYNAPTOPATHIE DANS UNE MALADIE NEURODÉGÉNÉRATIVE

Publication

EP 3765854 A1 20210120 (EN)

Application

EP 19709749 A 20190315

Priority

  • EP 18382175 A 20180316
  • EP 2019056535 W 20190315

Abstract (en)

[origin: WO2019175379A1] The present invention provides in vitro methods for the diagnosis and/or prognosis of synaptopathy and/or neurodegeneration in an individual, for deciding whether to initiate a therapeutic intervention, and for monitoring the efficacy of the therapeutic intervention, all based on the determination of the level of product expression of VAMP-2and/or Syntaxin-1.Advantageously, these markers allow the early detection of synaptopathy in diseases such as Alzheimer's disease.

IPC 8 full level

G01N 33/68 (2006.01)

CPC (source: EP)

G01N 33/6896 (2013.01); G01N 2800/52 (2013.01)

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2019175379 A1 20190919; EP 3765854 A1 20210120

DOCDB simple family (application)

EP 2019056535 W 20190315; EP 19709749 A 20190315