EP 3768703 A4 20220105 - ANTIBODIES BINDING PD-1 AND USES THEREOF
Title (en)
ANTIBODIES BINDING PD-1 AND USES THEREOF
Title (de)
PD-1-BINDENDE ANTIKÖRPER UND VERWENDUNGEN DAVON
Title (fr)
ANTICORPS DE LIAISON À PD-1 ET LEURS UTILISATIONS
Publication
Application
Priority
- US 201862657927 P 20180415
- US 201962795573 P 20190123
- CN 2019082447 W 20190412
Abstract (en)
[origin: WO2019201169A1] An isolated monoclonal antibody or an antigen-binding fragment that specifically binds human PD-1. A nucleic acid molecule encoding the antibody or the antigen-binding fragment, an expression vector, a host cell and a method for expressing the antibody or the antigen-binding fragment are also provided. The present invention further provides an immunoconjugate, a bispecific molecule, a chimeric antigen receptor, an oncolytic virus and a pharmaceutical composition comprising the antibody or the antigen-binding fragment, as well as a treatment method using an anti-PD-1 antibody of the invention.
IPC 8 full level
C07K 16/00 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP KR US)
A61K 39/39541 (2013.01 - US); A61K 45/06 (2013.01 - US); A61P 35/00 (2017.12 - EP KR US); C07K 16/2818 (2013.01 - EP KR US); A61K 2039/505 (2013.01 - EP KR US); C07K 2317/24 (2013.01 - EP KR US); C07K 2317/33 (2013.01 - EP KR); C07K 2317/565 (2013.01 - KR US); C07K 2317/76 (2013.01 - EP KR US); C07K 2317/92 (2013.01 - EP KR US)
Citation (search report)
- [X] WO 2018053709 A1 20180329 - WUXI BIOLOGICS SHANGHAI CO LTD [CN]
- [I] WO 2017058115 A1 20170406 - ASIA BIOTECH PTE LTD [SG]
- [AD] WO 2017019846 A1 20170202 - MACROGENICS INC [US]
- [A] WO 2018006005 A1 20180104 - ONCORUS INC [US]
- See references of WO 2019201169A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2019201169 A1 20191024; AU 2019254215 A1 20201022; CA 3097062 A1 20191024; CN 112074533 A 20201211; EP 3768703 A1 20210127; EP 3768703 A4 20220105; JP 2021520850 A 20210826; KR 20200143689 A 20201224; US 2021095032 A1 20210401
DOCDB simple family (application)
CN 2019082447 W 20190412; AU 2019254215 A 20190412; CA 3097062 A 20190412; CN 201980025195 A 20190412; EP 19788997 A 20190412; JP 2021504567 A 20190412; KR 20207030649 A 20190412; US 201917043809 A 20190412