EP 3774756 A1 20210217 - PROCESS FOR THE MANUFACTURE OF CHROMAN-6-OLS WITH SHORT SIDE CHAINS
Title (en)
PROCESS FOR THE MANUFACTURE OF CHROMAN-6-OLS WITH SHORT SIDE CHAINS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON CHROMAN-6-OLEN MIT KURZEN SEITENKETTEN
Title (fr)
PROCÉDÉ DE PRODUCTION DE CHROMAN-6-OLS À CHAÎNES LATÉRALES COURTES
Publication
Application
Priority
- EP 18164861 A 20180329
- EP 2019058064 W 20190329
Abstract (en)
[origin: WO2019185900A1] The present invention is directed to a process for the manufacture of a compound of formula (III), comprising the step of reacting a compound of formula (I) with a compound of formula (IIA), (IIB) or (IIC) in the presence of an acid catalyst and in a mixture of two solvents, wherein OR is OH, acetate, methanoate, propionate, butyrate or benzoate, A is CH2, R1 is C1-5-alkyl, R2 is either H or C1-2-alkyl, R4 is either H or C1-4-alkoxy or C1-4-alkyl, R3 and R5 are independently from each other either H or C1-4-alkyl, and the first of the two solvents is water, and the second of the two solvents is selected from aliphatic C5-8-hydrocarbons, cycloaliphatic C5-8-hydrocarbons, dialkyl ethers and methyl-substituted benzenes and any mixture thereof.
IPC 8 full level
C07D 311/72 (2006.01)
CPC (source: EP)
C07D 311/72 (2013.01)
Citation (search report)
See references of WO 2019185900A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2019185900 A1 20191003; CN 111936483 A 20201113; EP 3774756 A1 20210217
DOCDB simple family (application)
EP 2019058064 W 20190329; CN 201980023720 A 20190329; EP 19713808 A 20190329