EP 3775906 B1 20230830 - METABOLITE-BASED BREAST CANCER DETECTION AND DIAGNOSIS
Title (en)
METABOLITE-BASED BREAST CANCER DETECTION AND DIAGNOSIS
Title (de)
METABOLITEN-BASIERTE ERKENNUNG UND DIAGNOSE VON BRUSTKREBS
Title (fr)
DÉTECTION ET DIAGNOSTIC DU CANCER DU SEIN À BASE DE MÉTABOLITE
Publication
Application
Priority
- EP 18164999 A 20180329
- EP 2019057688 W 20190327
Abstract (en)
[origin: WO2019185692A1] The present invention relates to the use of a combination of metabolites contained in a sample of a mammalian subject in the in vitro or ex vivo early detection, diagnosis, prognosis and/or therapy monitoring of breast cancer. Said combination of metabolites comprises at least one amino acid selected from ornithine, threonine, tryptophane, glutamate, aspartate and histidine, at least one acylcarnitine and optionally further component(s). The present invention further relates to an in vitro or ex vivo method for the detection, diagnosis, prognosis and/or therapy monitoring of breast cancer, comprising providing a sample of a mammalian subject; determining the amount of a combination of metabolites; and comparing said amount with a control sample. The present invention further relates to a kit for performing said method.
IPC 8 full level
G01N 33/574 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
G01N 33/57415 (2013.01); G01N 33/6812 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2019185692 A1 20191003; EP 3775906 A1 20210217; EP 3775906 B1 20230830; EP 3775906 C0 20230830
DOCDB simple family (application)
EP 2019057688 W 20190327; EP 19712231 A 20190327