EP 3794029 A1 20210324 - COMPOSITIONS OF ISOLATED MONOCLONAL ANTIBODIES AND/OR ANTIGEN-BINDING FRAGMENTS THEREOF AGAINST INDOXYL SULFATE AND USES THEREOF
Title (en)
COMPOSITIONS OF ISOLATED MONOCLONAL ANTIBODIES AND/OR ANTIGEN-BINDING FRAGMENTS THEREOF AGAINST INDOXYL SULFATE AND USES THEREOF
Title (de)
ZUSAMMENSETZUNGEN VON ISOLIERTEN MONOKLONALEN ANTIKÖRPERN UND / ODER ANTIGEN-BINDENDEN FRAGMENTEN DAVON GEGEN INDOXYLSULFAT UND DEREN VERWENDUNGEN
Title (fr)
COMPOSITIONS D'ANTICORPS MONOCLONAUX ISOLÉS ET/OU DE FRAGMENTS DE LIAISON À L'ANTIGÈNE DE CEUX-CI CONTRE SULFATE D'INDOXYLE ET UTILISATIONS ASSOCIÉES
Publication
Application
Priority
- US 201862659256 P 20180418
- CN 2019083286 W 20190418
Abstract (en)
[origin: WO2019201311A1] The present invention provides isolated monoclonal antibodies (mAbs) and/or antigen-binding fragments thereof that specifically recognize indoxyl sulfate, a protein-bound uremic toxin, isolated polynucleotide segment encoding the isolated antibodies and/or antigen-binding fragments thereof, and uses of such isolated anti-IS mAbs and/or antigen-binding fragments thereof to create immunoassay methods, device compositions, and pharmaceutical compositions applied in theragnosis of IS-related diseases.
IPC 8 full level
C07K 16/18 (2006.01); A61K 39/395 (2006.01); A61P 13/12 (2006.01); G01N 33/53 (2006.01)
CPC (source: EP US)
A61P 13/12 (2017.12 - EP); A61P 39/00 (2017.12 - US); C07K 16/18 (2013.01 - US); C07K 16/44 (2013.01 - EP); G01N 33/5308 (2013.01 - US); G01N 33/6812 (2013.01 - EP); A61K 2039/505 (2013.01 - EP US); C07K 2317/92 (2013.01 - EP); G01N 2800/347 (2013.01 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2019201311 A1 20191024; CN 111741974 A 20201002; CN 111741974 B 20240116; EP 3794029 A1 20210324; EP 3794029 A4 20220112; JP 2021523694 A 20210909; JP 7366353 B2 20231023; TW 201943733 A 20191116; TW I710577 B 20201121; US 10723791 B2 20200728; US 11560423 B2 20230124; US 2020031909 A1 20200130; US 2020308263 A1 20201001
DOCDB simple family (application)
CN 2019083286 W 20190418; CN 201980014196 A 20190418; EP 19787626 A 20190418; JP 2020558504 A 20190418; TW 108113675 A 20190418; US 201916388622 A 20190418; US 202016902006 A 20200615