EP 3819298 A4 20210714 - COMPOUND HAVING TRKA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR ALLEVIATING PAIN, CONTAINING SAME AS ACTIVE INGREDIENT
Title (en)
COMPOUND HAVING TRKA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR ALLEVIATING PAIN, CONTAINING SAME AS ACTIVE INGREDIENT
Title (de)
VERBINDUNG MIT TRKA HEMMENDER WIRKUNG UND PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR VORBEUGUNG ODER LINDERUNG VON SCHMERZEN DAMIT ALS WIRKSTOFF
Title (fr)
COMPOSÉ AYANT UNE ACTIVITÉ INHIBITRICE DE TRKA ET COMPOSITION PHARMACEUTIQUE DESTINÉE À PRÉVENIR OU SOULAGER LA DOULEUR LE CONTENANT EN TANT QUE PRINCIPE ACTIF
Publication
Application
Priority
- KR 20180087092 A 20180726
- KR 2019006648 W 20190603
Abstract (en)
[origin: EP3819298A1] The present invention relates to a compound having TrkA inhibitory activity and a pharmaceutical composition for preventing or treating pain containing the same as an active ingredient. The compound provided in one aspect of the present invention has excellent TrkA inhibitory activity and exhibits excellent pain inhibitory effects in an animal model of pain after a surgery, and thus can be effectively used as an analgesic.
IPC 8 full level
C07D 471/04 (2006.01); A23L 33/10 (2016.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61P 25/00 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP KR US)
A23L 33/10 (2016.08 - EP KR US); A61K 31/437 (2013.01 - KR); A61K 31/4439 (2013.01 - KR); A61K 31/454 (2013.01 - KR); A61P 25/00 (2018.01 - EP KR); C07D 471/04 (2013.01 - EP KR US); C07D 487/04 (2013.01 - EP US); A23V 2002/00 (2013.01 - KR); A23V 2200/30 (2013.01 - KR); A61K 9/0019 (2013.01 - US); A61K 9/0053 (2013.01 - US); A61K 9/08 (2013.01 - US); A61K 9/1611 (2013.01 - US); A61K 9/1623 (2013.01 - US); A61K 9/2018 (2013.01 - US); A61K 9/2059 (2013.01 - US); A61K 9/4858 (2013.01 - US); A61K 47/26 (2013.01 - US)
Citation (search report)
- [XI] WO 2015143652 A1 20151001 - MERCK SHARP & DOHME [US], et al
- [XI] WO 2008112695 A2 20080918 - IRM LLC [US], et al
- [XI] WO 2015143653 A1 20151001 - MERCK SHARP & DOHME [US], et al
- See also references of WO 2020022636A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
EP 3819298 A1 20210512; EP 3819298 A4 20210714; EP 3819298 B1 20241030; CN 112533919 A 20210319; CN 112533919 B 20230616; JP 2021531350 A 20211118; JP 7132471 B2 20220907; KR 102129114 B1 20200702; KR 20200012168 A 20200205; US 2021309665 A1 20211007; WO 2020022636 A1 20200130
DOCDB simple family (application)
EP 19840528 A 20190603; CN 201980049772 A 20190603; JP 2021528310 A 20190603; KR 20180087092 A 20180726; KR 2019006648 W 20190603; US 201917261944 A 20190603