EP 3840737 A1 20210630 - COMPOSITIONS OF CLOFAZIMINE, COMBINATIONS COMPRISING THEM, PROCESSES FOR THEIR PREPARATION, USES AND METHODS COMPRISING THEM

Title (en)

COMPOSITIONS OF CLOFAZIMINE, COMBINATIONS COMPRISING THEM, PROCESSES FOR THEIR PREPARATION, USES AND METHODS COMPRISING THEM

Title (de)

CLOFAZIMIN-ZUSAMMENSETZUNGEN, DIESE ENTHALTENDE KOMBINATIONEN, VERFAHREN ZU IHRER HERSTELLUNG, IHRE VERWENDUNGEN UND VERFAHREN DAMIT

Title (fr)

COMPOSITIONS DE CLOFAZIMINE, COMBINAISONS LES COMPRENANT, LEURS PROCÉDÉS DE PRÉPARATION, UTILISATIONS ET PROCÉDÉS LES COMPRENANT

Publication

EP 3840737 A1 20210630 (EN)

Application

EP 19718942 A 20190403

Priority

US 201862722048 P 20180823
US 201962796822 P 20190125
US 2019025538 W 20190403

Abstract (en)

[origin: WO2020040818A1] The present invention relates to pharmaceutical compositions for inhalation comprising a therapeutically effective dose of clofazimine wherein the clofazimine is provided in the form of a suspension, and processes for their preparation. Furthermore, the present invention provides pharmaceutical combinations comprising clofazimine in the form of an aerosol for pulmonary inhalation. The combinations and compositions provided by the present invention may be used in the treatment and/or prophylaxis of pulmonary infections caused by mycobacteria and other gram-positive bacteria, and of pulmonary fungal infections.

IPC 8 full level

A61K 9/72 (2006.01); A61K 31/498 (2006.01); A61K 47/26 (2006.01)

CPC (source: EP KR)

A61K 9/0078 (2013.01 - EP KR); A61K 31/47 (2013.01 - EP KR); A61K 31/498 (2013.01 - EP KR); A61K 31/7036 (2013.01 - EP KR); A61K 45/06 (2013.01 - EP); A61K 47/02 (2013.01 - KR); A61K 47/26 (2013.01 - EP KR); A61P 11/00 (2018.01 - KR); A61P 31/10 (2018.01 - KR); A61K 2300/00 (2013.01 - KR)

C-Set (source: EP)

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2020040818 A1 20200227; AU 2019324330 A1 20210304; CA 3109572 A1 20200227; CN 112804993 A 20210514; EP 3840737 A1 20210630; JP 2021535124 A 20211216; JP 2024012393 A 20240130; JP 7377259 B2 20231109; KR 20210090607 A 20210720

DOCDB simple family (application)

US 2019025538 W 20190403; AU 2019324330 A 20190403; CA 3109572 A 20190403; CN 201980064766 A 20190403; EP 19718942 A 20190403; JP 2021510120 A 20190403; JP 2023184364 A 20231027; KR 20217007880 A 20190403