EP 3853354 A1 20210728 - MONONUCLEAR CELL DERIVED NK CELLS
Title (en)
MONONUCLEAR CELL DERIVED NK CELLS
Title (de)
AUS EINKERNIGEN ZELLEN ABGELEITETE NK-ZELLEN
Title (fr)
CELLULES NK DÉRIVÉES DE CELLULES MONONUCLÉAIRES
Publication
Application
Priority
US 2019040867 W 20190708
Abstract (en)
[origin: WO2021006875A1] Cord blood or peripheral blood NK cells are prepared from whole blood mononuclear cells without the need to isolate CD34+ hematopoietic stem cells or NK cells, and without the need for a feeder layer. Advantageously, the methods presented herein use an enrichment process that uses antiCD16 agonist antibodies, antiCD3 antibodies, and N-803. Moreover, contemplated processes are suitable for adaptation into a fully automated production process (GMP in a box).
IPC 8 full level
C12N 5/0783 (2010.01)
CPC (source: EP IL KR)
C12N 5/0646 (2013.01 - EP IL KR); C12N 2501/2315 (2013.01 - EP); C12N 2501/50 (2013.01 - KR); C12N 2501/515 (2013.01 - EP IL); C12N 2501/599 (2013.01 - EP IL); C12N 2506/11 (2013.01 - EP); C12N 2509/00 (2013.01 - KR)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2021006875 A1 20210114; AU 2019456283 A1 20210520; AU 2019456283 B2 20230608; CA 3120695 A1 20210114; CN 113166726 A 20210723; EP 3853354 A1 20210728; EP 3853354 A4 20220420; IL 283998 A 20210729; JP 2022513614 A 20220209; JP 2023040184 A 20230322; JP 7213976 B2 20230127; KR 20210080566 A 20210630; SG 11202104339W A 20210528
DOCDB simple family (application)
US 2019040867 W 20190708; AU 2019456283 A 20190708; CA 3120695 A 20190708; CN 201980078702 A 20190708; EP 19936966 A 20190708; IL 28399821 A 20210614; JP 2021527968 A 20190708; JP 2023001780 A 20230110; KR 20217018216 A 20190708; SG 11202104339W A 20190708