EP 3856905 A1 20210804 - METHODS AND COMPOSITIONS FOR INCREASING PROTEIN EXPRESSION AND/OR TREATING A HAPLOINSUFFICIENCY DISORDER
Title (en)
METHODS AND COMPOSITIONS FOR INCREASING PROTEIN EXPRESSION AND/OR TREATING A HAPLOINSUFFICIENCY DISORDER
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUR ERHÖHUNG DER PROTEINEXPRESSION UND/ODER BEHANDLUNG EINER HAPLOINSUFFIZIENZSTÖRUNG
Title (fr)
PROCÉDÉS ET COMPOSITIONS PERMETTANT D'AUGMENTER L'EXPRESSION DE PROTÉINES ET/OU DE TRAITER UN TROUBLE D'HAPLO-INSUFFISANCE
Publication
Application
Priority
- US 201862736847 P 20180926
- US 2019053268 W 20190926
Abstract (en)
[origin: WO2020069199A1] A tRNA that hybridizes to a non-optimal codon can be used to increase expression in a mammalian cell of a gene product encoded by a gene containing the non-optimal codon or to treat a haploinsufficiency disorder in a subject having a haploinsufficient gene containing the non-optimal codon.
IPC 8 full level
C12N 15/11 (2006.01); C12N 15/63 (2006.01); C12N 15/67 (2006.01)
CPC (source: EP KR US)
A61K 31/7088 (2013.01 - US); A61K 45/06 (2013.01 - US); A61K 48/00 (2013.01 - KR); A61K 48/0066 (2013.01 - US); A61P 25/08 (2017.12 - KR); A61P 43/00 (2017.12 - US); C12N 15/11 (2013.01 - US); C12N 15/113 (2013.01 - EP); C12N 15/67 (2013.01 - EP KR US); C12N 15/86 (2013.01 - US); C12N 2320/34 (2013.01 - EP); C12N 2330/51 (2013.01 - EP); C12N 2750/14143 (2013.01 - KR US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2020069199 A1 20200402; AU 2019350871 A1 20210520; BR 112021005788 A2 20211026; CA 3114109 A1 20200402; CL 2021000747 A1 20211022; CN 113195719 A 20210730; CO 2021005040 A2 20210920; EA 202190736 A1 20210916; EP 3856905 A1 20210804; EP 3856905 A4 20230621; IL 281848 A 20210531; JP 2022502044 A 20220111; KR 20210091699 A 20210722; MX 2021003567 A 20210824; US 2022073933 A1 20220310; ZA 202102302 B 20220428
DOCDB simple family (application)
US 2019053268 W 20190926; AU 2019350871 A 20190926; BR 112021005788 A 20190926; CA 3114109 A 20190926; CL 2021000747 A 20210325; CN 201980077435 A 20190926; CO 2021005040 A 20210420; EA 202190736 A 20190926; EP 19866182 A 20190926; IL 28184821 A 20210325; JP 2021517022 A 20190926; KR 20217012452 A 20190926; MX 2021003567 A 20190926; US 201917280369 A 20190926; ZA 202102302 A 20210407