EP 3873601 A1 20210908 - METHODS AND COMPOSITIONS FOR PREVENTING TYPE 1 DIABETES
Title (en)
METHODS AND COMPOSITIONS FOR PREVENTING TYPE 1 DIABETES
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUR PRÄVENTION VON DIABETES TYP 1
Title (fr)
PROCÉDÉS ET COMPOSITIONS POUR LA PRÉVENTION DU DIABÈTE DE TYPE 1
Publication
Application
Priority
- US 201962847466 P 20190514
- US 2020032891 W 20200514
Abstract (en)
[origin: CN112839707A] Provided herein, in one aspect, is a method of preventing or delaying the onset of clinical type 1 diabetes (T1D), comprising: providing a non-diabetic subject who is at risk for T1D; determining that the non-diabetic subject (1) is substantially free of antibodies against zinc transporter 8 (ZnT8), (2) is HLA-DR4+, and/or (3) is not HLA-DR3+; and administering a prophylactically effective amount of an anti-CD3 antibody to the non-diabetic subject.
IPC 8 full level
A61P 5/48 (2006.01); A61K 38/28 (2006.01); A61P 5/50 (2006.01)
CPC (source: EP)
A61P 5/48 (2017.12); A61P 5/50 (2017.12); C07K 16/2809 (2013.01); G01N 33/6854 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/24 (2013.01); C07K 2317/52 (2013.01); G01N 2800/52 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
CN 112839707 A 20210525; EP 3873601 A1 20210908; EP 3873601 A4 20220323
DOCDB simple family (application)
CN 202080005325 A 20200514; EP 20804811 A 20200514