EP 3902904 A1 20211103 - FLUIDIC SYSTEM FOR PRODUCING EXTRACELLULAR VESICLES AND ASSOCIATED METHOD
Title (en)
FLUIDIC SYSTEM FOR PRODUCING EXTRACELLULAR VESICLES AND ASSOCIATED METHOD
Title (de)
FLUIDISCHES SYSTEM ZUR HERSTELLUNG VON EXTRAZELLULÄREN VESIKELN UND ZUGEHÖRIGES VERFAHREN
Title (fr)
SYSTÈME FLUIDIQUE DE PRODUCTION DE VÉSICULES EXTRACELLULAIRES ET PROCÉDÉ ASSOCIÉ
Publication
Application
Priority
- FR 1874295 A 20181228
- FR 2019053309 W 20191227
Abstract (en)
[origin: WO2020136362A1] The invention relates to a fluidic system for producing extracellular vesicles (EV) from producer cells in suspension, comprising at least one container, a liquid medium contained in the container, producer cells in suspension, a liquid medium stirrer, means for controlling the speed of the stirrer suitable for the growth of the producer cells into suspension, characterized in that the means for controlling the speed of the stirrer, the stirrer and the shape and dimensions of the container are suitable for generating a turbulent flow of the liquid medium in the container for exerting shear stresses on the producer cells in order to carry out the production of extracellular vesicles (EV), the Kolmogorov length of the flow being less than or equal to 50 µm.
IPC 8 full level
C12M 1/06 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01)
CPC (source: EP KR US)
C12M 23/16 (2013.01 - US); C12M 23/34 (2013.01 - US); C12M 27/02 (2013.01 - EP KR US); C12M 29/04 (2013.01 - US); C12M 29/26 (2013.01 - KR); C12M 41/42 (2013.01 - EP KR); C12M 47/10 (2013.01 - EP KR); C12N 5/0635 (2013.01 - EP KR US); C12N 5/0693 (2013.01 - US); A61K 35/12 (2013.01 - KR); A61K 49/0097 (2013.01 - KR); C12N 2527/00 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2020136362 A1 20200702; CA 3124605 A1 20200702; CN 113748198 A 20211203; CN 113748198 B 20240412; EP 3902904 A1 20211103; FR 3091295 A1 20200703; FR 3091295 B1 20230526; JP 2022515269 A 20220217; KR 20210134611 A 20211110; MX 2021007776 A 20211013; US 2022119748 A1 20220421
DOCDB simple family (application)
FR 2019053309 W 20191227; CA 3124605 A 20191227; CN 201980093099 A 20191227; EP 19850769 A 20191227; FR 1874295 A 20181228; JP 2021537118 A 20191227; KR 20217023047 A 20191227; MX 2021007776 A 20191227; US 201917418970 A 20191227