EP 3902917 A2 20211103 - COMPOSITIONS AND METHODS FOR TREATING CANCER
Title (en)
COMPOSITIONS AND METHODS FOR TREATING CANCER
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON KREBS
Title (fr)
COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT DU CANCER
Publication
Application
Priority
- US 201862785592 P 20181227
- US 2019068423 W 20191223
Abstract (en)
[origin: WO2020139866A2] A double stranded RNA interference (RNAi) agent comprising at least one of (i) a first double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a CD320 gene wherein the first dsRNA comprises a sense strand and an antisense strand forming a duplex, (ii) a second dsRNA for inhibiting the expression of a LRP2 gene wherein the second dsRNA comprises a sense strand and an antisense strand forming a duplex, or (iii) a cocktail of (i) and (ii) and wherein the sense strand of the first dsRNA is at least substantially complementary to the antisense strand of the first dsRNA and the sense strand of the second dsRNA is at least substantially complementary to the antisense strand of the second dsRNA and the use of the RNAi agent as a pharmaceutical composition for the treatment of cancer in subjects in need of treatment.
IPC 8 full level
C12N 15/113 (2010.01); A61K 31/713 (2006.01); C07K 14/705 (2006.01)
CPC (source: EP)
C12N 15/1138 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2740/16043 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2020139866 A2 20200702; WO 2020139866 A3 20201015; CA 3163139 A1 20200702; CN 113508175 A 20211015; EP 3902917 A2 20211103; EP 3902917 A4 20221130
DOCDB simple family (application)
US 2019068423 W 20191223; CA 3163139 A 20191223; CN 201980093039 A 20191223; EP 19904756 A 20191223