EP 3934699 A1 20220112 - NEUROPROTECTIVE GENE THERAPY TARGETING THE AKT PATHWAY
Title (en)
NEUROPROTECTIVE GENE THERAPY TARGETING THE AKT PATHWAY
Title (de)
NEUROPROTEKTIVE GENTHERAPIE, DIE AUF DEN AKT-PFAD ABZIELT
Title (fr)
THÉRAPIE GÉNIQUE NEUROPROTECTRICE CIBLANT LA VOIE AKT
Publication
Application
Priority
- US 201962813587 P 20190304
- US 201962821705 P 20190321
- US 2020020832 W 20200303
Abstract (en)
[origin: WO2020180886A1] Compositions and methods for the treatment of retinal degeneration are provided. In one aspect, provided herein is adeno-associated virus (AAV) vector comprising an AAV capsid having encapsidated therein a vector genome comprising AAV inverted terminal repeat (ITR) sequences, a human protein kinase B (AKT) coding sequence, and expression control sequences that direct expression of AKT in a host cell.
IPC 8 full level
A61K 48/00 (2006.01); C07H 21/04 (2006.01); C12N 15/00 (2006.01)
CPC (source: EP KR US)
A61K 48/00 (2013.01 - KR); A61K 48/005 (2013.01 - EP US); A61P 27/02 (2017.12 - KR US); C12N 9/1205 (2013.01 - EP KR US); C12N 15/86 (2013.01 - EP KR US); C12Y 207/11001 (2013.01 - EP KR); A01K 2217/072 (2013.01 - EP); A01K 2227/105 (2013.01 - EP); A01K 2267/0306 (2013.01 - EP); C12N 2750/14143 (2013.01 - EP KR); C12Y 207/11001 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2020180886 A1 20200910; AU 2020232692 A1 20210930; CA 3131923 A1 20200910; CN 113795279 A 20211214; EP 3934699 A1 20220112; EP 3934699 A4 20221221; JP 2022524747 A 20220510; KR 20210141945 A 20211123; SG 11202109554X A 20210929; US 2022143217 A1 20220512
DOCDB simple family (application)
US 2020020832 W 20200303; AU 2020232692 A 20200303; CA 3131923 A 20200303; CN 202080033680 A 20200303; EP 20765810 A 20200303; JP 2021552552 A 20200303; KR 20217031245 A 20200303; SG 11202109554X A 20200303; US 202017435205 A 20200303