EP 3937936 A4 20221228 - INHIBITING CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB)
Title (en)
INHIBITING CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB)
Title (de)
HEMMUNG DES CYCLISCHEN AMP-RESPONSIVEN ELEMENT-BINDENDEN PROTEINS (CREB)
Title (fr)
INHIBITION DE LA PROTÉINE DE LIAISON À UN ÉLÉMENT SENSIBLE À L'AMP CYCLIQUE (CREB)
Publication
Application
Priority
- US 201962819482 P 20190315
- US 2020022783 W 20200313
Abstract (en)
[origin: WO2020190780A1] The present disclosure is directed to solid and salt forms of inhibitors of the CBP/p300 family of bromodomains made up of salts and crystalline forms of Formula (I). The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains (e.g., certain forms of cancer), and methods of synthesis of these compounds.
IPC 8 full level
C07D 471/04 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); A61K 31/4745 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP)
A61K 31/4745 (2013.01); C07D 471/04 (2013.01)
Citation (search report)
- [A] WO 2018073586 A1 20180426 - CELLCENTRIC LTD [GB]
- [A] MOSES MOUSTAKIM ET AL: "Discovery of a PCAF Bromodomain Chemical Probe", ANGEWANDTE CHEMIE, WILEY - V C H VERLAG GMBH & CO. KGAA, DE, vol. 129, no. 3, 14 December 2016 (2016-12-14), pages 845 - 849, XP071371206, ISSN: 0044-8249, DOI: 10.1002/ANGE.201610816
- See references of WO 2020190780A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2020190780 A1 20200924; AU 2020239990 A1 20211104; BR 112021016921 A2 20211103; CA 3132628 A1 20200924; CN 113874017 A 20211231; EP 3937936 A1 20220119; EP 3937936 A4 20221228; MX 2021010829 A 20211210
DOCDB simple family (application)
US 2020022783 W 20200313; AU 2020239990 A 20200313; BR 112021016921 A 20200313; CA 3132628 A 20200313; CN 202080028527 A 20200313; EP 20773477 A 20200313; MX 2021010829 A 20200313