Global Patent Index - EP 3947660 A4

EP 3947660 A4 20230125 - ENPP1 POLYPEPTIDES AND METHODS OF USING SAME

Title (en)

ENPP1 POLYPEPTIDES AND METHODS OF USING SAME

Title (de)

ENPP1-POLYPEPTIDE UND VERFAHREN ZU DEREN VERWENDUNG

Title (fr)

POLYPEPTIDES ENPP1 ET LEURS PROCÉDÉS D'UTILISATION

Publication

EP 3947660 A4 20230125 (EN)

Application

EP 20783595 A 20200403

Priority

  • US 202062983142 P 20200228
  • US 201962830230 P 20190405
  • US 202062984650 P 20200303
  • US 2020026643 W 20200403

Abstract (en)

[origin: WO2020206302A1] The present disclosure includes ENPP1 mutant polypeptides with improved in vivo half-lives.

IPC 8 full level

C12N 9/14 (2006.01); A61K 38/00 (2006.01); A61K 38/46 (2006.01); C07K 19/00 (2006.01); C12N 9/16 (2006.01); C12N 15/85 (2006.01)

CPC (source: EP IL KR US)

A61K 38/00 (2013.01 - KR); A61P 19/00 (2017.12 - KR); C07K 19/00 (2013.01 - IL); C12N 9/14 (2013.01 - EP IL KR US); C12N 9/16 (2013.01 - EP); C12N 15/85 (2013.01 - IL); C12Y 301/04001 (2013.01 - EP IL KR); C12Y 306/01009 (2013.01 - EP IL KR); A61K 38/00 (2013.01 - EP); C07K 2319/02 (2013.01 - EP US); C07K 2319/30 (2013.01 - EP IL KR US); C07K 2319/50 (2013.01 - EP US); C12Y 301/04001 (2013.01 - US); C12Y 306/01009 (2013.01 - US)

Citation (search report)

  • [A] WO 2016187408 A1 20161124 - UNIV YALE [US]
  • [A] ALBRIGHT RONALD A. ET AL: "ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy", NATURE COMMUNICATIONS, vol. 6, no. 1, 1 December 2015 (2015-12-01), XP055886466, Retrieved from the Internet <URL:https://www.nature.com/articles/ncomms10006.pdf> DOI: 10.1038/ncomms10006
  • [A] NITSCHKE YVONNE ET AL: "ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP", EXPERIMENTAL AND MOLECULAR MEDICINE, vol. 50, no. 10, 1 October 2018 (2018-10-01), KR, pages 1 - 12, XP055877818, ISSN: 1226-3613, Retrieved from the Internet <URL:https://www.nature.com/articles/s12276-018-0163-5.pdf> DOI: 10.1038/s12276-018-0163-5
  • [T] STABACH PAUL R. ET AL: "Improving the Pharmacodynamics and In Vivo Activity of ENPP1-Fc Through Protein and Glycosylation Engineering", CTS - CLINICAL AND TRANSLATIONAL SCIENCE, vol. 14, no. 1, 20 October 2020 (2020-10-20), US, pages 362 - 372, XP093005095, ISSN: 1752-8054, Retrieved from the Internet <URL:https://onlinelibrary.wiley.com/doi/full-xml/10.1111/cts.12887> DOI: 10.1111/cts.12887
  • See references of WO 2020206302A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2020206302 A1 20201008; AU 2020256253 A1 20211028; BR 112021020037 A2 20211207; CA 3136118 A1 20201008; CN 113993993 A 20220128; EP 3947660 A1 20220209; EP 3947660 A4 20230125; IL 286946 A 20211201; JP 2022527557 A 20220602; KR 20210149146 A 20211208; MX 2021012197 A 20220106; TW 202043292 A 20201201; US 2022195402 A1 20220623

DOCDB simple family (application)

US 2020026643 W 20200403; AU 2020256253 A 20200403; BR 112021020037 A 20200403; CA 3136118 A 20200403; CN 202080041580 A 20200403; EP 20783595 A 20200403; IL 28694621 A 20211004; JP 2021559256 A 20200403; KR 20217036178 A 20200403; MX 2021012197 A 20200403; TW 109111502 A 20200406; US 202017601387 A 20200403