EP 3964290 A1 20220309 - APPARATUS AND METHOD FOR PREPARING LIQUID SAMPLES FOR A SAMPLE ANALYSIS
Title (en)
APPARATUS AND METHOD FOR PREPARING LIQUID SAMPLES FOR A SAMPLE ANALYSIS
Title (de)
VORRICHTUNG UND VERFAHREN ZUR VORBEREITUNG VON FLÜSSIGKEITSPROBEN FÜR EINE PROBENANALYSE
Title (fr)
APPAREIL ET PROCÉDÉ DE PRÉPARATION D'ÉCHANTILLONS LIQUIDES POUR ANALYSE D'ÉCHANTILLONS
Publication
Application
Priority
EP 20194535 A 20200904
Abstract (en)
A sample preparing apparatus 100 for preparing a plurality of liquid samples 1 for a sample analysis, for instance for mass spectrometry, comprises a carrier plate device 10 with an array 11 of reaction sites 12, wherein the carrier plate device 10 is adapted for a first arrangement condition, wherein the reaction sites 12 are exposed and the carrier plate device 10 is configured for accommodating the samples 1 and supplying reagents to the liquid samples 1, and a collection device 20 comprising a collection vessel 21 with a vessel opening and a vessel bottom 23, wherein the collection vessel 21 is adapted for collecting the liquid samples 1 from at least two of the reaction sites 12 and providing the liquid samples 1 for the sample analysis, wherein the collection device 20 is adapted for a detachable connection with the carrier plate device 10, so that the vessel opening of the collection vessel 21 faces to the reaction sites 12, and the carrier plate device 10 is further adapted for a second arrangement condition, wherein the collection vessel 21 is connected with the carrier plate device 10 and the liquid samples 1 are capable to flow from the reaction sites 12 to the collection vessel 21 by the effect of a driving force. Furthermore, a sample preparing method for preparing a plurality of liquid samples 1 for a sample analysis is described, wherein the sample preparing apparatus 100 is used.
IPC 8 full level
CPC (source: EP)
B01L 3/50853 (2013.01); B01L 9/52 (2013.01); B01L 2300/046 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0822 (2013.01); B01L 2300/0829 (2013.01)
Citation (applicant)
- US 2019219592 A1 20190718 - BUDNIK BOGDAN [US], et al
- H. SPECHT ET AL., SINGLE-CELL MASS-SPECTROMETRY QUANTIFIES THE EMERGENCE OF MACROPHAGE HETEROGENEITY, Retrieved from the Internet <URL:http://dx.doi.org/10.1101/665307>
- Y. ZHU ET AL.: "Nanodroplet processing platform for deep and quantitative proteome profiling of 10-100 mammalian cells", NATURE COMMUNICATIONS, vol. 9, 2018, pages 882, XP055611613, DOI: 10.1038/s41467-018-03367-w
- Z. Y. LI ET AL.: "Nanoliter-Scale Oil-Air-Droplet Chip-Based Single Cell Proteomic Analysis", ANAL. CHEM., vol. 90, 2018, pages 5430 - 5438
- B. BUDNIK ET AL.: "SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation", GENOME BIOLOGY, vol. 19, 2018, pages 161, Retrieved from the Internet <URL:https://doi.org/1O.1186/s13059-018-1547-5>
Citation (search report)
- [XI] US 2003124029 A1 20030703 - WEBB BRIAN L [US], et al
- [XI] US 2018142195 A1 20180524 - LEE MOO-YEAL [US]
- [XI] US 2019119617 A1 20190425 - COLIN BRUNO [FR], et al
- [A] US 2011303027 A1 20111215 - SHIRAZI MOHSEN [US], et al
- [A] US 2014273053 A1 20140918 - LEE MOO-YEAL [US], et al
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DOCDB simple family (application)
EP 20194535 A 20200904