EP 3967335 A1 20220316 - ENGINEERED DEVITALIZED CARTILAGINOUS TISSUE FOR BONE REGENERATION
Title (en)
ENGINEERED DEVITALIZED CARTILAGINOUS TISSUE FOR BONE REGENERATION
Title (de)
MANIPULIERTES DEVITALISIERTES KNORPELGEWEBE ZUR KNOCHENREGENERATION
Title (fr)
TISSU CARTILAGINEUX DÉVITALISÉ MODIFIÉ POUR LA RÉGÉNÉRATION OSSEUSE
Publication
Application
Priority
EP 20195800 A 20200911
Abstract (en)
The invention is directed to a method for providing a devitalized cartilaginous tissue that is suitable for bone regeneration, said method comprising differentiating cells into vital cartilage cells to obtain a vital cartilaginous tissue and mildly devitalizing the vital tissue comprising drying, preferably lyophilizing, to obtain the devitalized cartilage tissue construct. Further aspects of the invention include tissue and constructs obtained by this method and use of said tissue and constructs in bone regeneration.
IPC 8 full level
A61L 27/24 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01)
CPC (source: EP)
A61L 27/24 (2013.01); A61L 27/3612 (2013.01); A61L 27/365 (2013.01); A61L 27/3691 (2013.01); A61L 27/3817 (2013.01); A61L 2430/02 (2013.01)
Citation (applicant)
- WO 2016160717 A1 20161006 - UNIV CALIFORNIA [US]
- GAWLITTA ET AL.: "Article 651", FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 8, 2020
- CUNNIFFE ET AL., ACTA BIOMATERIALIA, vol. 23, 2015, pages 82 - 90
- GAWLITTA ET AL., TISSUE ENGINEERING. PART A, vol. 21, 2015, pages 694 - 703
- PERRY ET AL.: "Experimental Biology 2016 Meeting Abstracts", THE FASEB JOURNAL, vol. 30, no. S1, April 2016 (2016-04-01), pages 9.2 - 9.2
- BOURGINE ET AL., PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 111, 2014, pages 17426 - 17431
- WHITE ET AL., ACTA BIOMATERIALIA, vol. 50, 2017, pages 207 - 219
- YUE ET AL., BIOMATERIALS, vol. 73, 2015, pages 254 - 271
- KLOTZ ET AL., TRENDS BIOTECHNOLOGY, vol. 34, 2016, pages 394 - 407
- GAWLITTA ET AL., TISSUE ENGINEERING PART A, vol. 18, 2012, pages 1957 - 66
- FARNDALE ET AL., BIOCHIMICA ET BIOPHYSICA ACTA, vol. 883, 1986, pages 173 - 7
- CREEMERS ET AL., BIOTECHNIQUES, vol. 22, 1997, pages 656 - 658
- GAWLITTA ET AL., TISSUE ENGINEERING PART A, vol. 21, 2015, pages 694 - 703
- VAN DER STOK ET AL., EUROPEAN CELLS AND MATERIALS, vol. 27, 2014, pages 137 - 48
Citation (search report)
- [A] WO 2018220047 A1 20181206 - TRAUMA CARE CONSULT [AT]
- [I] WO 2014033325 A1 20140306 - UNIVERSITAETSSPITAL BASEL RECHTSDIENST [CH]
- [A] RISBUD M V ET AL: "Tissue engineering: advances in in vitro cartilage generation", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 20, no. 8, 1 August 2002 (2002-08-01), pages 351 - 356, XP004371921, ISSN: 0167-7799, DOI: 10.1016/S0167-7799(02)02016-4
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
DOCDB simple family (application)
EP 20195800 A 20200911; NL 2021050554 W 20210913