Global Patent Index - EP 3973957 A1

EP 3973957 A1 20220330 - METHODS AND COMPOSITIONS TO INHIBIT SYMPTOMS ASSOCIATED WITH VEISALGIA

Title (en)

METHODS AND COMPOSITIONS TO INHIBIT SYMPTOMS ASSOCIATED WITH VEISALGIA

Title (de)

VERFAHREN UND ZUSAMMENSETZUNGEN ZUR HEMMUNG VON SYMPTOMEN IM ZUSAMMENHANG MIT VEISALGIA

Title (fr)

PROCÉDÉS ET COMPOSITIONS POUR INHIBER LES SYMPTÔMES ASSOCIÉS À LA VEISALGIE

Publication

EP 3973957 A1 20220330 (EN)

Application

EP 21208021 A 20160318

Priority

  • US 201562138665 P 20150326
  • EP 16769429 A 20160318
  • US 2016023200 W 20160318

Abstract (en)

The present invention relates to a method of reducing or preventing the symptoms associated with the intake of alcohol. The method comprises administering to a subject an effective amount of a pharmaceutical composition prior to alcohol intake. The pharmaceutical composition comprises a non-steroidal anti-inflammatory drug and a H<sub>1</sub>-antihistamine.

IPC 8 full level

A61K 31/10 (2006.01); A61K 9/00 (2006.01); A61K 31/192 (2006.01); A61K 31/196 (2006.01); A61K 31/407 (2006.01); A61K 31/445 (2006.01); A61K 31/473 (2006.01); A61K 31/60 (2006.01); A61K 45/06 (2006.01); A61P 1/02 (2006.01); A61P 3/02 (2006.01); A61P 29/00 (2006.01); A61P 39/02 (2006.01); A61P 43/00 (2006.01); A61K 31/4545 (2006.01); A61K 31/495 (2006.01); A61K 31/603 (2006.01)

CPC (source: EP IL KR US)

A61K 9/0056 (2013.01 - EP IL US); A61K 9/0058 (2013.01 - KR); A61K 9/20 (2013.01 - KR); A61K 31/12 (2013.01 - US); A61K 31/192 (2013.01 - EP IL KR US); A61K 31/196 (2013.01 - EP IL KR US); A61K 31/40 (2013.01 - US); A61K 31/405 (2013.01 - US); A61K 31/407 (2013.01 - EP IL KR US); A61K 31/445 (2013.01 - EP IL KR US); A61K 31/4545 (2013.01 - EP IL KR US); A61K 31/495 (2013.01 - EP IL KR US); A61K 31/5415 (2013.01 - US); A61K 31/60 (2013.01 - EP IL US); A61K 31/603 (2013.01 - EP IL US); A61K 31/616 (2013.01 - KR); A61K 45/06 (2013.01 - EP IL US); A61P 1/02 (2018.01 - EP); A61P 3/02 (2018.01 - EP); A61P 29/00 (2018.01 - EP KR US); A61P 39/02 (2018.01 - EP KR); A61P 43/00 (2018.01 - EP); A61K 2300/00 (2013.01 - IL KR)

C-Set (source: EP US)

  1. A61K 31/60 + A61K 2300/00
  2. A61K 31/192 + A61K 2300/00
  3. A61K 31/196 + A61K 2300/00
  4. A61K 31/603 + A61K 2300/00
  5. A61K 31/407 + A61K 2300/00
  6. A61K 31/445 + A61K 2300/00
  7. A61K 31/4545 + A61K 2300/00
  8. A61K 31/495 + A61K 2300/00

Citation (applicant)

  • US 201561138665 P
  • JORIS C. VERSTER: "The alcohol hangover-a puzzling phenomenon", ALCOHOL AND ALCOHOLISM, DOI:HTTP://DX.DOI.ORG/1 0. 1093/ALCALC/AGM 163, January 2008 (2008-01-01), pages 124 - 126
  • ROHSENOW ET AL.: "The role of beverage congeners in hangover and other residual effects of alcohol intoxication: a review", CURR DRUG ABUSE REV., vol. 3, no. 2, June 2010 (2010-06-01), pages 76 - 9, XP055685378, DOI: 10.2174/1874473711003020076
  • AMERICAN JOURNAL OF PREVENTIVE MEDICINE
  • PITTLER ET AL.: "Interventions for Preventing or Treating Alcohol Hangover: Systemic Review of Randomised Controlled Trials", BMJ, vol. 331, no. 7531, 24 December 2005 (2005-12-24), pages 1515 - 1518, XP008130029

Citation (search report)

Citation (examination)

VERSTER JORIS C ET AL: "The Effects of SJP-001 on Alcohol Hangover Severity: A Pilot Study", JOURNAL OF CLINICAL MEDICINE, vol. 9, no. 4, 31 March 2020 (2020-03-31), pages 932, XP055982383, ISSN: 2329-4590, DOI: 10.3390/jcm9040932

Citation (third parties)

Third party : Anonymous 18:50

  • T. BERL, A. RAZ, H. WALD, J. HOROWITZ, W. CZACZKES: "Prostaglandin synthesis inhibition and the action of vasopressin: studies in man and rat", AMERICAN JOURNAL OF PHYSIOLOGY: RENAL PHYSIOLOGY, AMERICAN PHYSIOLOGICAL SOCIETY, UNITED STATES, vol. 232, no. 6, 1 June 1977 (1977-06-01), United States , pages F529 - F537, XP055685334, ISSN: 1931-857X, DOI: 10.1152/ajprenal.1977.232.6.F529
  • B. EKLUND, L.A. CARLSON: "Central and peripheral circulatory effects and metabolic effects of different prostaglandins given I.V. to man", PROSTAGLANDINS., BUTTERWORTH, STONEHAM, MA., US, vol. 20, no. 2, 1 August 1980 (1980-08-01), US , pages 333 - 347, XP055685311, ISSN: 0090-6980, DOI: 10.1016/S0090-6980(80)80051-7
  • ANONYMOUS: "TOLERABLE UPPER INTAKE LEVELS FOR VITAMINS AND MINERALS", EUROPEAN FOOD SAFETY ASSOCIATION, 2006, XP055685386, Retrieved from the Internet <URL:https://www.efsa.europa.eu/sites/default/files/efsa_rep/blobserver_assets/ndatolerableuil.pdf>
  • GEORGE, F.R. ; COLLINS, A.C.: "Prostaglandin synthetase inhibitors antagonize the depressant effects of ethanol", PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR., ELSEVIER., US, vol. 10, no. 6, 1 June 1979 (1979-06-01), US , pages 865 - 869, XP025485403, ISSN: 0091-3057, DOI: 10.1016/0091-3057(79)90059-5
  • CARMICHAEL, J. ; SHANKEL, S.W.: "Effects of nonsteroidal anti-inflammatory drugs on prostaglandins and renal function", AMERICAN JOURNAL OF MEDICINE., EXCERPTA MEDICA, INC., UNITED STATES, vol. 78, no. 6, 1 June 1985 (1985-06-01), United States , pages 992 - 1000, XP023280064, ISSN: 0002-9343, DOI: 10.1016/0002-9343(85)90223-2

Third party : Anonymous 18:54

  • "Goodman & Gilman's Pharmacological Basis of Therapeutics", 1 January 2011, MCGRAW-HILL, article GOODMAN L., S.BRUNTON, L. L.CHABNER, B.KNOLLMANN, B. C.: "Renal actions of Vasopressin", pages: 707 - 708, XP055982385
  • J HAYLOR: "Prostaglandin synthesis and renal function in man", JOURNAL OF PHYSIOLOGY, vol. 298, no. 1, 1 January 1980 (1980-01-01), pages 383 - 396, XP055685328, DOI: 10.1113/jphysiol.1980.sp013088
  • S. KAIVOLA, J. PARANTAINEN, T. ÖSTERMAN, H. TIMONEN: "Hangover Headache and Prostaglandins: Prophylactic Treatment with Tolfenamic Acid", CEPHALALGIA, SAGE PUBLICATIONS LTD., GB, vol. 3, no. 1, 1 March 1983 (1983-03-01), GB , pages 31 - 36, XP055685325, ISSN: 0333-1024, DOI: 10.1046/j.1468-2982.1983.0301031.x
  • MAINTZ, L.NOVAK, N.: "Histamine and histamine intolerance", AM J CLIN NUTR, vol. 85, no. 5, 2007, pages 1185 - 1196, XP002466268
  • PARANTAINEN, J.: "Prostaglandins in alcohol intolerance and hangover", DRUG AND ALCOHOL DEPENDENCE, ELSEVIER SCIENTIFIC PUBLISHERS, IR, vol. 11, no. 3-4, 1 June 1983 (1983-06-01), IR , pages 239 - 248, XP023165730, ISSN: 0376-8716, DOI: 10.1016/0376-8716(83)90016-9
  • S. KAIVOLA, J. PARANTAINEN, T. ÖSTERMAN, H. TIMONEN: "Hangover Headache and Prostaglandins: Prophylactic Treatment with Tolfenamic Acid", CEPHALALGIA, SAGE PUBLICATIONS LTD., GB, vol. 3, no. 1, 1 March 1983 (1983-03-01), GB , pages 31 - 36, XP055685325, ISSN: 0333-1024, DOI: 10.1046/j.1468-2982.1983.0301031.x

Third party : Anonymous 18:56

  • EP 16769429 A 20160318
  • PITTLER MAX H; VERSTER JORIS C; ERNST EDZARD: "Interventions for preventing or treating alcohol hangover: systematic review of randomised controlled trials", BMJ. BRITISH MEDICAL JOURNAL., LONDON, GB, vol. 331, no. 7531, 24 December 2005 (2005-12-24), GB , pages 1515 - 1517, XP008130029, ISSN: 0959-8146
  • PENNING, R.MCKINNEY, A.VERSTER, J.C.: "Alcohol Hangover Symptoms and Their Contribution to the Overall Hangover Severity", ALCOHOL AND ALCOHOLISM, vol. 47, no. 3, 2012, pages 248 - 252, XP055685293, DOI: 10.1093/alcalc/ags029
  • PENNING, R.VAN NULAND, M.FLIERVOET, L.A.OLIVIER, B.VERSTER, J.C.: "The pathology of alcohol hangover", CURR DRUG ABUSE REV, vol. 3, no. 2, 2010, pages 68 - 75, XP055685400, DOI: 10.2174/1874473711003020068
  • PENNING, R.MCKINNEY, A.BUS, L.D.OLIVIER, B.SLOT, K.VERSTER, J.C.: "Measurement of alcohol hangover severity: development of the Alcohol Hangover Severity Scale (AHSS)", PSYCHOPHARMACOLOGY (BERL, vol. 225, no. 4, 2013, pages 803 - 810, XP055685391, DOI: 10.1007/s00213-012-2866-y
  • PRAT, G.ADAN, A.SANCHEZ-TURET, M.: "Alcohol hangover: a critical review of explanatory factors", HUM. PSYCHOPHARMACOL CLIN EXP, vol. 24, 2009, pages 259 - 267, XP055685375, DOI: 10.1002/hup.1023

Third party : Anonymous 18:59

  • I. RAMAEKERS, J.G., VERMEEREN, A.: "All antihistamines cross blood-brain barrier", BMJ, B M J GROUP, GB, vol. 321, no. 7260, 2 September 2000 (2000-09-02), GB , pages 572, XP055685337, ISSN: 0959-8138, DOI: 10.1136/bmj.321.7260.566
  • "Pharmacology. 7th ed.", 1 January 2012, article RANG, H. P., DALE M. M.: "26 Anti-inflammatory and immunosuppressant drugs", pages: 318 - 324, XP055685307
  • ROHSENOW, D.J.HOWLAND, J.: "The role of beverage congeners in hangover and other residual effects of alcohol intoxication a review", CURR DRUG ABUSE REV, vol. 3, no. 2, 2010, pages 76 - 79, XP055685378, DOI: 10.2174/1874473711003020076
  • SWIFT, R.DAVIDSON, D.: "Alcohol hangover mechanisms and mediators", ALCOHOL HEALTH RES WORLD, vol. 22, no. 1, 1998, pages 54 - 60, XP055685296
  • XIAOYU TAN, SUZANNE ESSENGUE, JAYA TALREJA, JEFF REESE, DANIEL J. STECHSCHULTE, KOTTARAPPAT N. DILEEPAN: "Histamine Directly and Synergistically with Lipopolysaccharide Stimulates Cyclooxygenase-2 Expression and Prostaglandin I 2 and E 2 Production in Human Coronary Artery Endothelial Cells", THE JOURNAL OF IMMUNOLOGY, WILLIAMS & WILKINS CO., US, vol. 179, no. 11, 1 December 2007 (2007-12-01), US , pages 7899 - 7906, XP055685330, ISSN: 0022-1767, DOI: 10.4049/jimmunol.179.11.7899
  • ROHSENOW, D.J.HOWLAND, J.: "The role of beverage congeners in hangover and other residual effects of alcohol intoxication: a review", CURR DRUG ABUSE REV, vol. 3, no. 2, 2010, pages 76 - 79, XP055685378, DOI: 10.2174/1874473711003020076
  • ROBERT SWIFT, DENA DAVIDSON: "Alcohol hangover: mechanisms and mediators", ALCOHOL HEALTH & RESEARCH WORLD, vol. 22, no. 1, 1 February 1998 (1998-02-01), pages 54 - 60, XP055685296
  • TAN, X.ESSENGUE, S.TALREJA, J.REESE, J.STECHSCHULTE, D.J.DILEEPAN, K.N.: "Histamine directly and synergistically with lipopolysaccharide stimulates cyclooxygenase-2 expression and prostaglandin 1(2) and E(2) production in human coronary artery endothelial cells", J IMMUNOL, vol. 179, no. 11, 2007, pages 7899 - 7906, XP055685330, DOI: 10.4049/jimmunol.179.11.7899

Third party : Anonymous 19:05

  • VERMEEREN, A.O'HANLON, J.F.: "Fexofenadine's effects, alone and with alcohol, on actual driving and psychomotor performance", J ALLERGY CLIN IMMUNOL, vol. 101, no. 3, 1998, pages 306 - 311, XP027420962, DOI: 10.1016/S0091-6749(98)70240-4
  • VERSTER JORIS C, DAHL THOMAS A, SCHOLEY ANDREW, IVERSEN JACQUELINE M: "The Effects of SJP-001 on Alcohol Hangover Severity: A Pilot Study", JOURNAL OF CLINICAL MEDICINE, vol. 9, no. 4, 31 March 2020 (2020-03-31), pages 932, XP055982383, ISSN: 2329-4590, DOI: 10.3390/jcm9040932
  • VERSTER, J. C., VAN DE LOO, A., BENSON, S., SCHOLEY, A., STOCK, A. K.: "The Assessment of Overall Hangover Severity ", JOURNAL OF CLINICAL MEDICINE, vol. 9, no. 3, 2020, pages 786, XP055787819
  • JORIS C. VERSTER, RENSKE PENNING: "Treatment and Prevention of Alcohol Hangover", CURRENT DRUG ABUSE REVIEWSE, BENTHAM SCIENCE PUBLISHERS LTD, vol. 3, no. 2, 1 June 2010 (2010-06-01), pages 103 - 109, XP055685298, ISSN: 1874-4737, DOI: 10.2174/1874473711003020103
  • WIESE, J.G.SHLIPAK, M.G.BROWNER, W.S.: "The Alcohol Hangover", ANNALS OF INTERNAL MEDICINE, vol. 132, no. 11, 2000, pages 897 - 902, XP055787807

Third party : Anonymous 19:10

ZIMATKIN, S.M., ANICHTCHIK, O.V.: "Alcohol-histamine interactions", ALCOHOL & ALCOHOLISM, vol. 34, no. 2, 1 March 1999 (1999-03-01), pages 141 - 147, XP055685338, DOI: 10.1093/alcalc/34.2.141

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

US 10420756 B2 20190924; US 2016279112 A1 20160929; AU 2016235484 A1 20171012; AU 2016235484 B2 20210218; BR 112017020307 A2 20180605; BR 112017020307 B1 20231107; CA 2980162 A1 20160929; CA 2980162 C 20240618; CN 107635549 A 20180126; CN 115887456 A 20230404; EP 3273952 A1 20180131; EP 3273952 A4 20181121; EP 3273952 B1 20220615; EP 3973957 A1 20220330; ES 2926494 T3 20221026; IL 254641 A0 20171130; IL 254641 B1 20230901; IL 254641 B2 20240101; JP 2018509470 A 20180405; JP 6851365 B2 20210331; KR 102597910 B1 20231102; KR 20170131647 A 20171129; MX 2017012132 A 20180706; MX 2022001796 A 20220317; NZ 735777 A 20230331; PL 3273952 T3 20221114; US 11464766 B2 20221011; US 2020009119 A1 20200109; US 2023064685 A1 20230302; WO 2016154028 A1 20160929; ZA 201706794 B 20190227

DOCDB simple family (application)

US 201615074524 A 20160318; AU 2016235484 A 20160318; BR 112017020307 A 20160318; CA 2980162 A 20160318; CN 201680030862 A 20160318; CN 202211634942 A 20160318; EP 16769429 A 20160318; EP 21208021 A 20160318; ES 16769429 T 20160318; IL 25464117 A 20170924; JP 2018501141 A 20160318; KR 20177031097 A 20160318; MX 2017012132 A 20160318; MX 2022001796 A 20170925; NZ 73577716 A 20160318; PL 16769429 T 20160318; US 2016023200 W 20160318; US 201916573384 A 20190917; US 202217902124 A 20220902; ZA 201706794 A 20171009