Global Patent Index - EP 3976038 A1

EP 3976038 A1 20220406 - HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS

Title (en)

HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS

Title (de)

HETEROCYCLISCHE VERBINDUNGEN ALS PRMT5-INHIBITOREN

Title (fr)

COMPOSÉS HÉTÉROCYCLIQUES EN TANT QU'INHIBITEURS DE PRMT5

Publication

EP 3976038 A1 20220406 (EN)

Application

EP 20814821 A 20200527

Priority

  • US 201962854435 P 20190530
  • US 202062966337 P 20200127
  • US 2020034711 W 20200527

Abstract (en)

[origin: WO2020243178A1] The present disclosure describes novel heterocyclic PRMT5 inhibitors and methods for preparing them. The pharmaceutical compositions comprising such PRMT5 inhibitors and methods of using them for treating cancer, infectious diseases, and other PRMT5 associated disorders are also described.

IPC 8 full level

A61K 31/4725 (2006.01); A61K 31/496 (2006.01); A61K 31/498 (2006.01)

CPC (source: EP KR)

A61K 31/519 (2013.01 - KR); A61K 31/7064 (2013.01 - KR); A61P 31/00 (2017.12 - EP KR); A61P 35/00 (2017.12 - EP KR); C07D 487/04 (2013.01 - EP KR); C07D 519/00 (2013.01 - EP); C07H 19/14 (2013.01 - EP KR)

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2020243178 A1 20201203; AU 2020283505 A1 20211223; CA 3141855 A1 20201203; CN 114126614 A 20220301; EP 3976038 A1 20220406; EP 3976038 A4 20230712; JP 2022534998 A 20220804; KR 20220016194 A 20220208

DOCDB simple family (application)

US 2020034711 W 20200527; AU 2020283505 A 20200527; CA 3141855 A 20200527; CN 202080052198 A 20200527; EP 20814821 A 20200527; JP 2021570954 A 20200527; KR 20217043087 A 20200527