Global Patent Index - EP 3980126 A1

EP 3980126 A1 20220413 - BENZO[H][1,6] NAPHTHYRIDIN-2(1H)-ONES AS BMX INHIBITORS, FOR USE AGAINST CANCER

Title (en)

BENZO[H][1,6] NAPHTHYRIDIN-2(1H)-ONES AS BMX INHIBITORS, FOR USE AGAINST CANCER

Title (de)

BENZO[H][1,6]NAPHTHYRIDIN-2(1H)-ONE ALS BMX-INHIBITOREN ZUR VERWENDUNG GEGEN KREBS

Title (fr)

BENZO[H][1,6] NAPHTYRIDIN-2(1H)-ONES UTILISÉS EN TANT QU'INHIBITEURS DE BMX DESTINÉS À ÊTRE UTILISÉS CONTRE LE CANCER

Publication

EP 3980126 A1 20220413 (EN)

Application

EP 20732523 A 20200605

Priority

  • GB 201908171 A 20190607
  • EP 2020065730 W 20200605

Abstract (en)

[origin: WO2020245430A1] The present invention provides a compound of formula (I) and its use in methods of treatment, including the treatment of cancer. The compound has the structure shown below where D is an acceptor group and -A-, -L-, R7 are as discussed in the application: Formula (1a). The present invention also provides a compound of formula (II) and its use in methods of treatment including the treatment of cancer. The compound has the structure shown below where D is an acceptor group and -A-, -L-, R6 are as discussed in the application Formula (1b).

IPC 8 full level

A61P 35/00 (2006.01); A61K 31/4745 (2006.01); A61K 31/496 (2006.01); A61K 31/5377 (2006.01); C07D 471/04 (2006.01)

CPC (source: CN EP)

A61P 19/02 (2017.12 - CN); A61P 35/00 (2017.12 - CN EP); A61P 37/06 (2017.12 - CN); C07D 471/04 (2013.01 - CN EP)

Citation (search report)

See references of WO 2020245430A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

WO 2020245430 A1 20201210; AU 2020288706 A1 20220106; CA 3140767 A1 20201210; CN 114206867 A 20220318; EP 3980126 A1 20220413; GB 201908171 D0 20190724

DOCDB simple family (application)

EP 2020065730 W 20200605; AU 2020288706 A 20200605; CA 3140767 A 20200605; CN 202080054085 A 20200605; EP 20732523 A 20200605; GB 201908171 A 20190607