EP 3985014 A4 20240410 - ROMO1-DERIVED ANTIMICROBIAL PEPTIDES AND VARIANTS THEREOF
Title (en)
ROMO1-DERIVED ANTIMICROBIAL PEPTIDES AND VARIANTS THEREOF
Title (de)
ROMO1-ABGELEITETE ANTIMIKROBIELLE PEPTIDE UND VARIANTEN DAVON
Title (fr)
PEPTIDES ANTIMICROBIENS DÉRIVÉS DE ROMO1 ET VARIANTS DE CEUX-CI
Publication
Application
Priority
- KR 20190071635 A 20190617
- KR 2020007802 W 20200617
Abstract (en)
[origin: EP3985014A1] The present invention relates to antimicrobial peptides derived from Romol protein, and specifically, provides various peptides having the amino acid sequence of the α-helix 2 region of the Romol protein and an antibacterial composition containing each of the peptides, as a result of confirming that the peptides have antibacterial activity against gram-positive, gram-negative and multidrug-resistant bacteria. The Romol-derived peptides and variants thereof according to the present invention have better bactericidal capability against various types of bacteria and multidrug-resistant bacteria than existing antibiotics and antibiotic peptides, and in particular, have antibacterial activity against various bacteria in blood vessels, and thus are novel antibiotics that may be provided as substances for the prevention or treatment of a wide range of bacterial infectious diseases. Thus, a composition containing the antimicrobial peptide of the present invention is expected to be used in various applications, including drugs, quasi-drugs, food and feed additives, pesticide and cosmetic additives, to prevent or treat infectious diseases.
IPC 8 full level
A01N 37/46 (2006.01); A23K 20/147 (2016.01); A23L 33/18 (2016.01); A61K 8/64 (2006.01); A61K 38/00 (2006.01); A61P 31/04 (2006.01); A61Q 17/00 (2006.01); C07K 7/08 (2006.01)
CPC (source: EP KR US)
A01N 33/08 (2013.01 - KR); A01N 37/46 (2013.01 - EP); A01N 63/50 (2020.01 - EP); A01P 1/00 (2021.08 - EP); A23K 20/147 (2016.05 - KR); A23K 20/195 (2016.05 - KR); A23L 3/34635 (2013.01 - KR); A23L 33/18 (2016.08 - KR); A61K 8/64 (2013.01 - EP KR); A61K 38/00 (2013.01 - KR); A61K 38/1709 (2013.01 - US); A61P 31/00 (2018.01 - US); A61P 31/04 (2018.01 - EP KR US); A61Q 17/005 (2013.01 - KR); A61Q 19/00 (2013.01 - EP); C07K 7/08 (2013.01 - KR); C07K 14/47 (2013.01 - EP); A23K 20/147 (2016.05 - EP); A23K 20/195 (2016.05 - EP); A23L 33/127 (2016.08 - EP); A23L 33/18 (2016.08 - EP); A23V 2002/00 (2013.01 - KR); A61K 38/00 (2013.01 - EP); A61K 2800/10 (2013.01 - EP); Y02A 50/30 (2018.01 - EP)
Citation (search report)
- [X] EP 1693381 A1 20060823 - BEIJING INST OF RADIATION MEDI [CN]
- [X] CN 1699416 A 20051123 - INST OF RADIATION MEDICINE THE [CN]
- [X] CN 1699409 A 20051123 - INST OF RADIATION MEDICINE THE [CN]
- [X] US 2005272067 A1 20051208 - MACINA ROBERTO A [US], et al
- [X] DATABASE GenPept [online] NCBI; 31 October 2014 (2014-10-31), "PREDICTED: reactive oxygen species modulator 1, partial [Nestor notabilis].", XP002810674, retrieved from EBI accession no. UPI000523B9A6 Database accession no. XP_010010134
- See also references of WO 2020256387A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 3985014 A1 20220420; EP 3985014 A4 20240410; CN 114269771 A 20220401; CN 114341160 A 20220412; EP 3985013 A1 20220420; EP 3985013 A4 20240124; JP 2022538545 A 20220905; JP 2022538546 A 20220905; JP 7315724 B2 20230726; JP 7386905 B2 20231127; KR 102499670 B1 20230220; KR 102544364 B1 20230619; KR 20200144065 A 20201228; KR 20200144066 A 20201228; US 2022362331 A1 20221117; US 2022362332 A1 20221117; WO 2020256387 A1 20201224; WO 2020256392 A1 20201224
DOCDB simple family (application)
EP 20827933 A 20200617; CN 202080058005 A 20200617; CN 202080058256 A 20200617; EP 20826226 A 20200617; JP 2021575444 A 20200617; JP 2021575448 A 20200617; KR 20200072111 A 20200615; KR 20200072112 A 20200615; KR 2020007802 W 20200617; KR 2020007816 W 20200617; US 202017619913 A 20200617; US 202017619918 A 20200617