EP 3986932 A1 20220427 - MONOCLONAL ANTIBODY TARGETING A UNIQUE CANCER-ASSOCIATED EPITOPE OF CD43
Title (en)
MONOCLONAL ANTIBODY TARGETING A UNIQUE CANCER-ASSOCIATED EPITOPE OF CD43
Title (de)
GEGEN EIN EINDEUTIGES KREBSASSOZIIERTES EPITOP VON CD43 GERICHTETER MONOKLONALER ANTIKÖRPER
Title (fr)
ANTICORPS MONOCLONAL CIBLANT UN ÉPITOPE DE CD43 ASSOCIÉ À UN CANCER UNIQUE
Publication
Application
Priority
- US 201916449255 A 20190621
- EP 2020067258 W 20200619
Abstract (en)
[origin: WO2020254670A1] The present invention relates to a monoclonal mouse antibody produced by the hybridoma cell deposited under ICLC accession number ICLC PD n° 16001. Furthermore, the invention relates to an antibody comprising a heavy chain variable region comprising complementarity determining regions CDRH1, CDRH2 and CDRH3, and a light chain variable region comprising complementarity determining regions CDRL1, CDRL2 and CDRL3, wherein CDRH1, CDRH2, CDRH3, CDRL1, CDRL2, and CDRL3 comprise the amino acid sequences GFTFSSFGMH (SEQ ID NO: 1), YISSGSGNFYYVDTVKG (SEQ ID NO: 43), STYYHGSRGAMDY (SEQ ID NO: 3), SASSSVSSMYWY (SEQ ID NO: 4), DTSKMAS (SEQ ID NO: 5), and QQWSSYPPIT (SEQ ID NO: 6), respectively. In addition, the invention relates to antibodies recognizing the same epitope.
IPC 8 full level
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01); G01N 33/574 (2006.01)
CPC (source: CN EP IL KR US)
A61K 35/02 (2013.01 - IL US); A61K 38/00 (2013.01 - IL); A61K 39/4611 (2023.05 - CN EP IL KR); A61K 39/4631 (2023.05 - CN EP IL KR); A61K 39/464499 (2023.05 - CN EP IL KR); A61K 47/6849 (2017.08 - IL US); A61K 47/6851 (2017.08 - IL US); A61P 35/00 (2018.01 - CN EP IL KR US); A61P 35/02 (2018.01 - CN EP IL); C07K 14/7051 (2013.01 - CN IL US); C07K 14/70521 (2013.01 - IL US); C07K 14/70578 (2013.01 - IL US); C07K 16/2809 (2013.01 - CN EP IL US); C07K 16/2896 (2013.01 - CN EP IL KR US); C07K 16/3092 (2013.01 - CN EP IL); G01N 33/57407 (2013.01 - IL US); G01N 33/57492 (2013.01 - CN EP IL KR); A61K 38/00 (2013.01 - US); A61K 2039/505 (2013.01 - CN EP IL KR US); A61K 2039/55 (2013.01 - CN EP IL); C07K 14/7051 (2013.01 - EP); C07K 2317/24 (2013.01 - IL US); C07K 2317/31 (2013.01 - CN EP IL KR US); C07K 2317/34 (2013.01 - CN EP IL KR); C07K 2317/41 (2013.01 - CN EP IL KR); C07K 2317/565 (2013.01 - IL US); C07K 2317/622 (2013.01 - CN EP IL KR US); C07K 2317/73 (2013.01 - CN EP IL); C07K 2317/732 (2013.01 - CN EP IL KR US); C07K 2319/02 (2013.01 - IL US); C07K 2319/03 (2013.01 - CN EP IL); C07K 2319/30 (2013.01 - IL US); C07K 2319/33 (2013.01 - IL US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2020254670 A1 20201224; AU 2020298104 A1 20220224; BR 112021025908 A2 20220621; CA 3143891 A1 20201224; CN 114651011 A 20220621; EP 3986932 A1 20220427; IL 289082 A 20220201; JP 2022537419 A 20220825; KR 20220116141 A 20220822; MX 2021015915 A 20220406
DOCDB simple family (application)
EP 2020067258 W 20200619; AU 2020298104 A 20200619; BR 112021025908 A 20200619; CA 3143891 A 20200619; CN 202080059251 A 20200619; EP 20734312 A 20200619; IL 28908221 A 20211216; JP 2021576099 A 20200619; KR 20227002369 A 20200619; MX 2021015915 A 20200619