EP 4001263 B1 20240327 - CARBAMATE-SUBSTITUTED STYRYL SULFONE COMPOUND, PREPARATION METHOD, AND APPLICATION THEREOF
Title (en)
CARBAMATE-SUBSTITUTED STYRYL SULFONE COMPOUND, PREPARATION METHOD, AND APPLICATION THEREOF
Title (de)
CARBAMATSUBSTITUIERTE STYRYLSULFONVERBINDUNG, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
Title (fr)
COMPOSÉ STYRYLSULFONE À SUBSTITUTION CARBAMATE, SON PROCÉDÉ DE PRÉPARATION ET SON APPLICATION
Publication
Application
Priority
CN 2019096502 W 20190718
Abstract (en)
[origin: EP4001263A1] The invention relates to carbamate-substituted styryl sulfone compounds and preparation methods and uses thereof. The carbamate-substituted styryl sulfone compounds of the invention have a structure of general formula (I). The compound of the invention not only has a significantly enhanced acetylcholinesterase inhibitory activity compared with carbamates as positive drugs, but also has a significantly enhanced therapeutic effect on Parkinson's disease compared with caffeic acid phenethyl ester compounds having similar structures.
IPC 8 full level
C07C 317/18 (2006.01); A61P 25/16 (2006.01); C07C 317/28 (2006.01); C07D 207/08 (2006.01); C07D 213/643 (2006.01); C07D 265/30 (2006.01); C07D 295/205 (2006.01); C07D 333/36 (2006.01); C07F 7/18 (2006.01)
CPC (source: CN EP US)
A61P 25/16 (2018.01 - CN EP); C07C 317/18 (2013.01 - CN EP); C07C 317/28 (2013.01 - CN EP US); C07D 207/08 (2013.01 - CN EP US); C07D 213/643 (2013.01 - CN EP US); C07D 265/30 (2013.01 - CN EP US); C07D 295/205 (2013.01 - EP); C07D 295/215 (2013.01 - CN); C07D 307/38 (2013.01 - CN); C07D 307/54 (2013.01 - US); C07D 333/36 (2013.01 - CN EP US); C07F 7/1804 (2013.01 - CN EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 4001263 A1 20220525; EP 4001263 A4 20230315; EP 4001263 B1 20240327; EP 4001263 C0 20240327; CN 114072380 A 20220218; CN 114072380 B 20240315; CN 118239868 A 20240625; JP 2022541047 A 20220921; JP 7324930 B2 20230810; US 2022267263 A1 20220825; WO 2021007840 A1 20210121
DOCDB simple family (application)
EP 19937580 A 20190718; CN 2019096502 W 20190718; CN 201980098207 A 20190718; CN 202410332465 A 20190718; JP 2022503475 A 20190718; US 201917628017 A 20190718