EP 4007587 A1 20220608 - A METHOD AND A COMPOUND FOR PREVENTING MAMMALIAN CANCER CELL PROLIFERATION AND FOR TREATING CANCER
Title (en)
A METHOD AND A COMPOUND FOR PREVENTING MAMMALIAN CANCER CELL PROLIFERATION AND FOR TREATING CANCER
Title (de)
VERFAHREN UND VERBINDUNG ZUR VORBEUGUNG VON KREBSZELLPROLIFERATION BEI SÄUGERN UND ZUR BEHANDLUNG VON KREBS
Title (fr)
MÉTHODE ET COMPOSÉ POUR LA PRÉVENTION DE LA PROLIFÉRATION DE CELLULES CANCÉREUSES DE MAMMIFÈRES ET POUR LE TRAITEMENT DU CANCER
Publication
Application
Priority
- FI 20195656 A 20190802
- FI 20205195 A 20200226
- FI 2020050513 W 20200803
Abstract (en)
[origin: WO2021023914A1] A composition and a method for use in suppressing growth and/or proliferation of cancer cells in vivo and in vitro is provided. The composition includes an alcoholic lignan extract prepared from coniferous species optionally in combination with betulonic acid or betulinic acid. The composition inhibits growth and/or proliferation of at least prostate and melanoma cancer cells in vitro. Combination of the alcoholic lignan extract and betulonic or betulinic acid has a synergic effect specifically in inhibition of melanoma and prostate cancer cell proliferation and toxicity. Oral daily administration of the composition decreases or in some cases abolishes tumors of patients with breast cancer, brain cancer or colon cancer. The composition is suitable for use in cancer treatment in pet animals as well.
IPC 8 full level
A61K 36/15 (2006.01); A61K 31/065 (2006.01); A61K 31/34 (2006.01); A61P 35/00 (2006.01); C07C 15/14 (2006.01); C07D 307/06 (2006.01); C07D 307/33 (2006.01)
CPC (source: EP)
A61K 31/09 (2013.01); A61K 31/19 (2013.01); A61K 31/341 (2013.01); A61K 31/365 (2013.01); A61K 36/15 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2017.12); A61K 2236/00 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2021023914 A1 20210211; AU 2020326319 A1 20220317; CA 3149681 A1 20210211; EP 4007587 A1 20220608; EP 4007587 A4 20230927
DOCDB simple family (application)
FI 2020050513 W 20200803; AU 2020326319 A 20200803; CA 3149681 A 20200803; EP 20850158 A 20200803