EP 4013789 A4 20231122 - ANTIBODIES BINDING VISTA AND USES THEREOF
Title (en)
ANTIBODIES BINDING VISTA AND USES THEREOF
Title (de)
VISTA BINDENDE ANTIKÖRPER UND VERWENDUNGEN DAVON
Title (fr)
ANTICORPS SE LIANT À VISTA ET LEURS UTILISATIONS
Publication
Application
Priority
- US 201916541193 A 20190815
- CN 2020107214 W 20200805
Abstract (en)
[origin: US10577424B1] An isolated monoclonal antibody or the antigen binding portion thereof that specifically binds human VISTA. A nucleic acid molecule encoding the antibody, an expression vector, a host cell and a method for expressing the antibody or the antigen binding portion thereof are also provided. The present disclosure further provides a bispecific molecule, and a pharmaceutical composition comprising the antibody or the binding moieties thereof, as well as a treatment method using an anti-VISTA antibody or the antigen binding portion thereof of the present disclosure.
IPC 8 full level
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01); C12N 15/13 (2006.01); C12N 15/85 (2006.01)
CPC (source: CN EP US)
A61K 31/513 (2013.01 - EP); A61K 31/555 (2013.01 - EP); A61K 31/704 (2013.01 - EP); A61K 38/193 (2013.01 - EP); A61K 38/2026 (2013.01 - EP); A61K 39/3955 (2013.01 - US); A61K 39/39558 (2013.01 - US); A61K 45/06 (2013.01 - EP US); A61P 31/00 (2017.12 - CN); A61P 35/00 (2017.12 - CN EP US); A61P 35/02 (2017.12 - CN); C07K 16/28 (2013.01 - US); C07K 16/2818 (2013.01 - EP); C07K 16/2827 (2013.01 - CN EP US); C12N 15/85 (2013.01 - CN); A61K 2039/505 (2013.01 - CN US); A61K 2039/507 (2013.01 - US); C07K 16/18 (2013.01 - US); C07K 16/2803 (2013.01 - US); C07K 2317/24 (2013.01 - CN EP US); C07K 2317/31 (2013.01 - CN US); C07K 2317/33 (2013.01 - EP); C07K 2317/56 (2013.01 - US); C07K 2317/565 (2013.01 - US); C07K 2317/75 (2013.01 - EP); C07K 2317/76 (2013.01 - US); C07K 2317/92 (2013.01 - US)
Citation (search report)
- [I] WO 2019078699 A2 20190425 - PHARMABCINE INC [KR] & EP 3699193 A2 20200826 - PHARMABCINE INC [KR]
- [I] US 2017320950 A1 20171109 - SNYDER LINDA A [US], et al
- [I] WO 2018237287 A1 20181227 - APEXIGEN INC [US]
- See references of WO 2021027662A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 10577424 B1 20200303; CN 111004327 A 20200414; CN 111004327 B 20210413; EP 4013789 A1 20220622; EP 4013789 A4 20231122; WO 2021027662 A1 20210218
DOCDB simple family (application)
US 201916541193 A 20190815; CN 201911423791 A 20191231; CN 2020107214 W 20200805; EP 20851508 A 20200805