EP 4021477 A1 20220706 - METHODS OF GENERATING AND ISOLATING MIDBRAIN DOPAMINE NEURONS
Title (en)
METHODS OF GENERATING AND ISOLATING MIDBRAIN DOPAMINE NEURONS
Title (de)
VERFAHREN ZUM ERZEUGEN UND ISOLIEREN VON MID-DOPAMIN-NEURONEN
Title (fr)
PROCÉDÉS DE GÉNÉRATION ET D'ISOLATION DE NEURONES DOPAMINERGIQUES MÉSENCÉPHALES
Publication
Application
Priority
- US 201962893674 P 20190829
- US 2020048733 W 20200831
Abstract (en)
[origin: WO2021042027A1] The present disclosure provides methods for generating midbrain dopamine neurons (mDAs) and precursors thereof, mDAs and precursors thereof generated by such methods and compositions comprising such cells, and uses thereof for preventing and/or treating neurological disorders. The present disclosure further provides methods of isolating mDAs and precursors thereof from a cell population using novel surface markers.
IPC 8 full level
A61K 38/14 (2006.01)
CPC (source: EP IL KR US)
A61K 35/30 (2013.01 - KR US); A61K 35/545 (2013.01 - EP IL); A61P 25/28 (2018.01 - KR); C12N 5/0619 (2013.01 - EP IL KR US); C12N 2501/115 (2013.01 - EP); C12N 2501/119 (2013.01 - EP IL KR US); C12N 2501/15 (2013.01 - EP IL KR US); C12N 2501/155 (2013.01 - EP); C12N 2501/16 (2013.01 - EP US); C12N 2501/41 (2013.01 - EP US); C12N 2501/415 (2013.01 - EP IL KR US); C12N 2506/02 (2013.01 - KR US); C12N 2506/03 (2013.01 - KR); C12N 2506/45 (2013.01 - US)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2021042027 A1 20210304; AU 2020336221 A1 20220407; BR 112022003826 A2 20220531; CA 3152522 A1 20210304; CN 114650836 A 20220621; EP 4021477 A1 20220706; EP 4021477 A4 20231213; IL 290930 A 20220401; JP 2022546482 A 20221104; KR 20220051388 A 20220426; MX 2022002532 A 20220616; US 2022177835 A1 20220609; ZA 202202994 B 20221221
DOCDB simple family (application)
US 2020048733 W 20200831; AU 2020336221 A 20200831; BR 112022003826 A 20200831; CA 3152522 A 20200831; CN 202080075663 A 20200831; EP 20856169 A 20200831; IL 29093022 A 20220227; JP 2022513499 A 20200831; KR 20227010271 A 20200831; MX 2022002532 A 20200831; US 202217681113 A 20220225; ZA 202202994 A 20220311