Global Patent Index - EP 4029505 A1

EP 4029505 A1 20220720 - INJECTION CONTAINING P-BORONOPHENYLALANINE

Title (en)

INJECTION CONTAINING P-BORONOPHENYLALANINE

Title (de)

P-BORONOPHENYLALANIN ENTHALTENDE INJEKTION

Title (fr)

INJECTION CONTENANT DE LA P-BORONOPHÉNYLALANINE

Publication

EP 4029505 A1 20220720 (EN)

Application

EP 20863900 A 20200909

Priority

  • JP 2019165979 A 20190912
  • JP 2020034086 W 20200909

Abstract (en)

An object of the present invention is to provide an injection solution for boron neutron capture therapy. Provided is an injection solution for boron neutron capture therapy, containing p-boronophenylalanine or a pharmaceutically acceptable salt thereof, with a ratio of boron 10 of boron atoms in a compound of 75 % or more; a sugar alcohol; an antioxidant; and water, the injection solution having a pH of 6.5 to 7.8 and an osmotic pressure ratio of 1.0 to 1.8, the injection solution being to be administered by intravenous drip injection.

IPC 8 full level

A61K 31/69 (2006.01); A61K 9/08 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61P 35/00 (2006.01); C07F 5/02 (2006.01)

CPC (source: CN EP KR US)

A61K 9/0014 (2013.01 - CN); A61K 9/0019 (2013.01 - EP US); A61K 9/08 (2013.01 - CN EP KR); A61K 31/69 (2013.01 - EP KR US); A61K 41/0095 (2013.01 - CN US); A61K 47/02 (2013.01 - CN EP KR US); A61K 47/10 (2013.01 - US); A61K 47/26 (2013.01 - CN EP KR); A61P 35/00 (2018.01 - CN EP KR US); C07F 5/02 (2013.01 - CN); A61K 41/0095 (2013.01 - KR)

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

DOCDB simple family (publication)

EP 4029505 A1 20220720; EP 4029505 A4 20231011; AR 119936 A1 20220119; AU 2020347682 A1 20220421; CA 3151009 A1 20210318; CN 114423458 A 20220429; JP WO2021049520 A1 20210318; KR 20220062367 A 20220516; TW 202114717 A 20210416; US 2022280540 A1 20220908; WO 2021049520 A1 20210318

DOCDB simple family (application)

EP 20863900 A 20200909; AR P200102517 A 20200910; AU 2020347682 A 20200909; CA 3151009 A 20200909; CN 202080064227 A 20200909; JP 2020034086 W 20200909; JP 2021545564 A 20200909; KR 20227012002 A 20200909; TW 109131216 A 20200911; US 202017753658 A 20200909