EP 4041872 A4 20231025 - DEVELOPMENT OF A NOVEL LIVE ATTENUATED AFRICAN SWINE FEVER VACCINE BASED IN THE DELETION OF GENE I177L
Title (en)
DEVELOPMENT OF A NOVEL LIVE ATTENUATED AFRICAN SWINE FEVER VACCINE BASED IN THE DELETION OF GENE I177L
Title (de)
ENTWICKLUNG EINES NEUEN ABGESCHWÄCHTEN LEBENDIMPFSTOFFS GEGEN DIE AFRIKANISCHE SCHWEINEPEST BASIEREND AUF DER DELETION DES GENS I177L
Title (fr)
DÉVELOPPEMENT D'UN NOUVEAU VACCIN VIVANT ATTÉNUÉ CONTRE LA PESTE PORCINE AFRICAINE BASÉ SUR LA DÉLÉTION DU GÈNE I177L
Publication
Application
Priority
- US 201916580058 A 20190924
- US 2020022569 W 20200313
Abstract (en)
[origin: US2021085776A1] Provided herein are details on the construction of a recombinant African Swine Fever Virus (ASFV) live attenuated vaccine for prevention of ASF caused by various strains of ASFV, such as the highly virulent Georgia 2007 isolate (“ASFV-G”). An exemplary vaccine comprises the ASFV-GΔI1771 modified virus, a recombinant ASFV-G modified by deleting a portion of the I177L ORF rendering the I177L gene nonfunctional.
IPC 8 full level
C12N 7/00 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61P 31/20 (2006.01)
CPC (source: EP KR US)
A61K 39/12 (2013.01 - EP KR US); A61P 31/20 (2017.12 - EP KR US); C12N 7/00 (2013.01 - KR); A61K 2039/5254 (2013.01 - EP KR US); C12N 2710/12034 (2013.01 - EP KR)
Citation (search report)
- [XYI] WO 2018005358 A1 20180104 - US AGRICULTURE [US], et al
- [Y] BORCA MANUEL V ET AL: "CRISPR-Cas9, a tool to efficiently increase the development of recombinant African swine fever viruses", SCIENTIFIC REPORTS, vol. 8, 16 February 2018 (2018-02-16), XP009547831
- See references of WO 2021061189A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 11007263 B2 20210518; US 2021085776 A1 20210325; AU 2020354864 A1 20220512; BR 112022005143 A2 20220816; CA 3155856 A1 20210401; CL 2022000563 A1 20230113; CN 114555793 A 20220527; CO 2022004992 A2 20220429; EP 4041872 A1 20220817; EP 4041872 A4 20231025; JP 2022549425 A 20221125; KR 20220097391 A 20220707; MX 2022003435 A 20220614; US 11813319 B2 20231114; US 2021244809 A1 20210812; WO 2021061189 A1 20210401
DOCDB simple family (application)
US 201916580058 A 20190924; AU 2020354864 A 20200313; BR 112022005143 A 20200313; CA 3155856 A 20200313; CL 2022000563 A 20220307; CN 202080073072 A 20200313; CO 2022004992 A 20220421; EP 20868193 A 20200313; JP 2022518213 A 20200313; KR 20227013262 A 20200313; MX 2022003435 A 20200313; US 2020022569 W 20200313; US 202117223252 A 20210406