EP 4053117 A1 20220907 - ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS
Title (en)
ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS
Title (de)
ARYL, HETEROARYL UND HETEROCYCLISCHE VERBINDUNGEN ZUR BEHANDLUNG VON MEDIZINISCHEN ERKRANKUNGEN
Title (fr)
COMPOSÉS ARYLES, HÉTÉROARYLES ET HÉTÉROCYCLIQUES POUR LE TRAITEMENT DES TROUBLES MÉDICAUX
Publication
Application
Priority
- US 201562209972 P 20150826
- EP 16840121 A 20160825
- US 2016048696 W 20160825
Abstract (en)
Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula I, or a pharmaceutically acceptable salt or composition thereof wherein R<sup>12</sup> or R<sup>13</sup> on the A group is an aryl, heteroaryl or heterocycle (R<sup>32</sup>) are provided. The inhibitors of Factor D described herein reduce the excessive activation of complement.
IPC 8 full level
C07D 401/14 (2006.01); A61P 1/16 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 493/04 (2006.01); C07D 495/04 (2006.01); C07D 513/04 (2006.01)
CPC (source: CN EA EP IL KR RU US)
A61K 31/167 (2013.01 - EA); A61K 31/395 (2013.01 - EA); A61K 31/40 (2013.01 - EA); A61K 31/416 (2013.01 - EA KR RU); A61K 31/4439 (2013.01 - EA KR RU); A61K 31/444 (2013.01 - EA); A61K 31/497 (2013.01 - EA); A61K 31/506 (2013.01 - EA KR RU); A61K 31/519 (2013.01 - EA KR RU); A61P 1/16 (2018.01 - CN EA EP IL KR RU); A61P 3/06 (2018.01 - EP IL RU); A61P 9/00 (2018.01 - CN EA EP IL RU); A61P 9/10 (2018.01 - EP IL RU); A61P 11/00 (2018.01 - CN EA EP IL RU); A61P 13/00 (2018.01 - EA EP IL KR RU); A61P 13/02 (2018.01 - EP IL RU); A61P 17/00 (2018.01 - CN EP IL RU); A61P 19/02 (2018.01 - CN EA EP IL RU); A61P 21/00 (2018.01 - CN EP IL RU); A61P 25/00 (2018.01 - EA EP IL RU); A61P 25/02 (2018.01 - EP IL RU); A61P 27/00 (2018.01 - EA EP IL RU); A61P 27/02 (2018.01 - CN EA EP IL RU); A61P 29/00 (2018.01 - CN EP IL RU); A61P 37/02 (2018.01 - CN); A61P 43/00 (2018.01 - EP IL RU); C07D 401/14 (2013.01 - EA EP IL KR RU US); C07D 403/06 (2013.01 - EA EP IL RU US); C07D 403/14 (2013.01 - EA EP IL KR RU US); C07D 405/14 (2013.01 - EA EP IL RU US); C07D 409/14 (2013.01 - EA EP IL RU US); C07D 413/14 (2013.01 - EA EP IL RU US); C07D 417/14 (2013.01 - EA EP IL KR RU US); C07D 471/04 (2013.01 - EA EP IL RU US); C07D 487/04 (2013.01 - EA EP IL KR RU US); C07D 493/04 (2013.01 - EA EP IL RU US); C07D 495/04 (2013.01 - EA EP IL RU US); C07D 513/04 (2013.01 - EA EP IL RU US); C07K 5/06191 (2013.01 - CN); A61K 38/00 (2013.01 - CN); Y02A 50/30 (2018.01 - EP)
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Citation (search report)
- [I] WO 2014002057 A1 20140103 - NOVARTIS AG [CH], et al
- [I] US 2012295884 A1 20121122 - ALTMANN EVA [CH], et al
- [A] US 2005267108 A1 20051201 - HSIEH HSING-PANG [TW], et al
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