EP 4055005 A1 20220914 - LIQUID MELPHALAN COMPOSITION
Title (en)
LIQUID MELPHALAN COMPOSITION
Title (de)
FLÜSSIGE MELPHALANZUSAMMENSETZUNG
Title (fr)
COMPOSITION LIQUIDE DE MELPHALAN
Publication
Application
Priority
- IB 2020060334 W 20201104
- IN 201921044683 A 20191104
Abstract (en)
[origin: WO2021090183A1] The present invention related to a stable liquid pharmaceutical composition comprising melphalan or its pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable excipients, wherein the said stable liquid pharmaceutical composition is first diluted with a diluent vehicle to provide a stable ready to dilute pharmaceutical composition of melphalan or its pharmaceutically acceptable salts thereof. The said stable ready to dilute pharmaceutical composition is further diluted to obtain a final diluted melphalan composition before administering to the patient in need thereof. Further, the present invention provides process for the preparation of the said composition and its use for the treatment of multiple myeloma.
IPC 8 full level
C07C 229/36 (2006.01); A61K 9/08 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP)
A61K 9/08 (2013.01); A61K 31/198 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/20 (2013.01); A61P 35/00 (2017.12); C07C 227/44 (2013.01); A61K 9/0019 (2013.01)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
DOCDB simple family (publication)
WO 2021090183 A1 20210514; EP 4055005 A1 20220914; EP 4055005 A4 20231129
DOCDB simple family (application)
IB 2020060334 W 20201104; EP 20886165 A 20201104