Global Patent Index - EP 4055176 A4

EP 4055176 A4 20240417 - ANTI-GUCY2C VACCINES AND VACCINATION

Title (en)

ANTI-GUCY2C VACCINES AND VACCINATION

Title (de)

ANTI-GUCY2C-IMPFSTOFFE UND IMPFUNG

Title (fr)

VACCINS ANTI-GUCY2C ET VACCINATION

Publication

EP 4055176 A4 20240417 (EN)

Application

EP 20960974 A 20201109

Priority

  • US 202062932499 P 20201107
  • US 202062933361 P 20201108
  • US 2020059752 W 20201109

Abstract (en)

[origin: WO2022098372A1] Compositions comprising a modified adenovirus AD5.F35 which includes coding sequence of soluble GUCY2C extracellular domain sequences are disclosed. Compositions comprising a Listeria monocytogenes vector which includes coding sequence of soluble GUCY2C extracellular domain sequences are disclosed. Methods of treating individuals diagnosed with cancer/tumors expressing GUCY2C methods of preventing micro-metastasis are disclosed.

IPC 8 full level

C12N 15/861 (2006.01); A61K 35/76 (2015.01); A61K 48/00 (2006.01); C12N 5/10 (2006.01); C12N 7/00 (2006.01); C12N 15/09 (2006.01); C12N 15/86 (2006.01)

CPC (source: EP)

A61K 39/001154 (2018.08); C12N 9/88 (2013.01); C12N 15/86 (2013.01); C12Y 406/01002 (2013.01); A61K 2039/522 (2013.01); A61K 2039/525 (2013.01); A61K 2039/545 (2013.01); A61K 2039/572 (2013.01); C12N 2710/10343 (2013.01); C12N 2800/22 (2013.01)

Citation (search report)

  • [XAI] SNOOK ADAM E. ET AL: "Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients", JOURNAL FOR IMMUNOTHERAPY OF CANCER, vol. 7, no. 1, 23 April 2019 (2019-04-23), pages 1 - 12, XP055939172, Retrieved from the Internet <URL:http://link.springer.com/article/10.1186/s40425-019-0576-2/fulltext.html> DOI: 10.1186/s40425-019-0576-2
  • [IA] SNOOK ADAM: "Metastatic Colorectal Cancer Immunotherapy with GUCY2C-Expressing Listeria monocytogenes", PROJECT REPORT, 1 September 2018 (2018-09-01), pages 45pp, XP055939177, Retrieved from the Internet <URL:https://apps.dtic.mil/sti/citations/AD1062516> [retrieved on 20220706]
  • See also references of WO 2022098372A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2022098372 A1 20220512; AU 2020475819 A1 20220623; EP 4055176 A1 20220914; EP 4055176 A4 20240417

DOCDB simple family (application)

US 2020059752 W 20201109; AU 2020475819 A 20201109; EP 20960974 A 20201109