Global Patent Index - EP 4079331 A1

EP 4079331 A1 20221026 - VEGETABLE OIL-DERIVED CONTRAST AGENT WITH HIGH STABILITY AND PREPARATION METHOD THEREOF

Title (en)

VEGETABLE OIL-DERIVED CONTRAST AGENT WITH HIGH STABILITY AND PREPARATION METHOD THEREOF

Title (de)

AUS PFLANZENÖL GEWONNENES KONTRASTMITTEL MIT HOHER STABILITÄT UND HERSTELLUNGSVERFAHREN DAFÜR

Title (fr)

AGENT DE CONTRASTE DÉRIVÉ D'HUILE VÉGÉTALE PRÉSENTANT UNE GRANDE STABILITÉ ET SON PROCÉDÉ DE PRÉPARATION

Publication

EP 4079331 A1 20221026 (EN)

Application

EP 21174808 A 20210519

Priority

KR 20210052133 A 20210422

Abstract (en)

One embodiment of the present disclosure provides a contrast agent containing an iodinated unsaturated fatty acid ethyl ester derived from vegetable oil, a non-iodinated unsaturated fatty acid ethyl ester, and sulfur dioxide (SO<sub>2</sub>), and a production method thereof.According to the present disclosure, a contrast agent having a similar contrast effect is synthesized using vegetable oil as a substitute for poppy seed oil, which is unstable in terms of supply and is expensive. In addition, the long-term stability problem of an iodine-based contrast agent is solved by adding a non-iodinated unsaturated fatty acid ethyl ester and sulfur dioxide.

IPC 8 full level

A61K 49/04 (2006.01)

CPC (source: EP US)

A61K 49/0438 (2013.01 - EP US)

Citation (search report)

  • [Y] EP 0198344 A1 19861022 - MERCK PATENT GMBH [DE]
  • [Y] JP 2014068541 A 20140421 - CHIKUNO SHOKUHIN KOGYO KK
  • [Y] EP 3428256 A1 20190116 - FOOD INDUSTRY RES & DEV INST [TW]
  • [A] CN 107287029 A 20171024 - JIANGSU HENGRUI MEDICINE CO
  • [Y] GIESE J: "ANTIOXIDANTS: TOOLS FOR PREVENTING LIPID OXIDATION ANTIOXIDANTS ARECRITICAL IN PRESERVING LIPID-CONTAINING FOODS FROM RANCIDITY AND EXTENDING SHELF LIFE", FOOD TECHNOLOGY, INSTITUTE OF FOOD TECHNOLOGISTS, CHICAGO, IL, US, vol. 50, no. 11, 1 November 1996 (1996-11-01), XP000640468, ISSN: 0015-6639
  • [Y] "ENCYCLOPEDIA OF PHARMACEUTICAL TECHNOLOGY Third Ed.", vol. 43, 1 January 2006, ISBN: 978-0-8493-9399-0, article SANDEEP NEMA ET AL: "Excipients: Parenteral Dosage Forms and Their Role", pages: 1622 - 1645, XP055640522

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

Designated validation state (EPC)

KH MA MD TN

DOCDB simple family (publication)

EP 4079331 A1 20221026; KR 102335099 B1 20211206; US 2022339299 A1 20221027

DOCDB simple family (application)

EP 21174808 A 20210519; KR 20210052133 A 20210422; US 202117319912 A 20210513