EP 4082531 A1 20221102 - OPHTHALMIC SUSPENSION COMPOSITION
Title (en)
OPHTHALMIC SUSPENSION COMPOSITION
Title (de)
OPHTHALMISCHE SUSPENSIONSZUSAMMENSETZUNG
Title (fr)
COMPOSITION DE SUSPENSION OPHTALMIQUE
Publication
Application
Priority
- US 201562107696 P 20150126
- EP 20166312 A 20160126
- EP 18209003 A 20160126
- EP 16704744 A 20160126
- US 2016014872 W 20160126
Abstract (en)
A suspension includes an ophthalmic active ingredient suspended in a formulation vehicle including a suspending agent and a non-ionic cellulose derivative. The ophthalmic active agent is present as particles having D<sub>v90</sub> < 5 µm and D<sub>v50</sub>< 1 µm. The suspension may be administered to a patient for treating an ophthalmic inflammatory condition.
IPC 8 full level
A61K 9/14 (2006.01); A61K 31/56 (2006.01); A61K 31/573 (2006.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01); A61K 47/38 (2006.01)
CPC (source: CN EP KR US)
A61K 9/0048 (2013.01 - CN EP KR US); A61K 9/10 (2013.01 - CN KR); A61K 9/14 (2013.01 - US); A61K 9/146 (2013.01 - CN EP KR US); A61K 31/56 (2013.01 - CN EP KR US); A61K 31/573 (2013.01 - CN EP KR US); A61K 47/02 (2013.01 - KR US); A61K 47/06 (2013.01 - KR US); A61K 47/10 (2013.01 - CN EP KR US); A61K 47/32 (2013.01 - CN EP KR US); A61K 47/38 (2013.01 - CN EP KR US); A61P 27/02 (2018.01 - EP US)
Citation (applicant)
- US 5538721 A 19960723 - BABCOCK JOHN C [US], et al
- US 4540930 A 19850910 - SIEDBAND MELVIN P [US]
- US 4996335 A 19910226 - BODOR NICHOLAS S [US]
- US 4615697 A 19861007 - ROBINSON JOSEPH R [US]
- WO 8906964 A1 19890810 - INSITE VISION INC [US]
- US 5192535 A 19930309 - DAVIS JEFFREY P [US], et al
- LIU ET AL.: "Nanosuspensions of poorly soluble drugs: preparation and development by wet milling", INT. J. OF PHARM, vol. 411, 2011, pages 215 - 222, XP055143914, DOI: 10.1016/j.ijpharm.2011.03.050
- SCHOENWALD RDHARRIS RGURNER D ET AL.: "Ophthalmic bioequivalence of steroid/antibiotic combination formulations", BIOPHARM DRUG DISPOS, vol. 8, 1987, pages 527 - 548
- TANG-LIU DDBURKE PJ: "The effect of azone on ocular levobunolol absorption: calculating the area under the curve and its standard error using tissue sampling compartments", PHARM RES, vol. 5, 1988, pages 238 - 241
Citation (search report)
- [A] US 2014328917 A1 20141106 - TADA TAKAHIRO [JP], et al
- [A] US 2013303502 A1 20131114 - CAVANAGH THOMAS [US], et al
- [A] EP 0659433 A1 19950628 - SENJU PHARMA CO [JP], et al
- [A] WO 2004006959 A1 20040122 - ELAN PHARMA INT LTD [IE]
- [A] WO 2013043387 A1 20130328 - BAUSCH & LOMB [US], et al
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
US 10596107 B2 20200324; US 2016213609 A1 20160728; AU 2016211745 A1 20170831; AU 2021203027 A1 20210610; AU 2021203027 B2 20230713; AU 2023248145 A1 20231102; BR 112017016016 A2 20180320; BR 112017016016 B1 20231219; CA 2975106 A1 20160804; CN 107427464 A 20171201; CN 107427464 B 20220405; EP 3250185 A1 20171206; EP 3250185 B1 20181205; EP 3470059 A1 20190417; EP 3470059 B1 20200401; EP 3721868 A1 20201014; EP 3721868 B1 20220601; EP 4082531 A1 20221102; EP 4082531 B1 20231011; EP 4268850 A1 20231101; ES 2704125 T3 20190314; ES 2787039 T3 20201014; ES 2924645 T3 20221010; ES 2966595 T3 20240423; HU E041945 T2 20190628; HU E048564 T2 20200828; HU E059639 T2 20221228; JP 2018507252 A 20180315; KR 102538370 B1 20230601; KR 20170105610 A 20170919; MX 2017009699 A 20171023; PL 3250185 T3 20190531; PL 3470059 T3 20201130; PL 3721868 T3 20221107; PL 4082531 T3 20240408; PT 3721868 T 20220812; PT 4082531 T 20231214; US 11534395 B2 20221227; US 2020214977 A1 20200709; US 2023140895 A1 20230511; WO 2016123079 A1 20160804
DOCDB simple family (application)
US 201615006525 A 20160126; AU 2016211745 A 20160126; AU 2021203027 A 20210512; AU 2023248145 A 20231012; BR 112017016016 A 20160126; CA 2975106 A 20160126; CN 201680016825 A 20160126; EP 16704744 A 20160126; EP 18209003 A 20160126; EP 20166312 A 20160126; EP 22175139 A 20160126; EP 23196938 A 20160126; ES 16704744 T 20160126; ES 18209003 T 20160126; ES 20166312 T 20160126; ES 22175139 T 20160126; HU E16704744 A 20160126; HU E18209003 A 20160126; HU E20166312 A 20160126; JP 2017558359 A 20160126; KR 20177023453 A 20160126; MX 2017009699 A 20160126; PL 16704744 T 20160126; PL 18209003 T 20160126; PL 20166312 T 20160126; PL 22175139 T 20160126; PT 20166312 T 20160126; PT 22175139 T 20160126; US 2016014872 W 20160126; US 202016826366 A 20200323; US 202218086286 A 20221221