EP 4087654 A1 20221116 - TREATMENT OF ALZHEIMER'S DISEASE
Title (en)
TREATMENT OF ALZHEIMER'S DISEASE
Title (de)
BEHANDLUNG VON MORBUS ALZHEIMER
Title (fr)
TRAITEMENT DE LA MALADIE D'ALZHEIMER
Publication
Application
Priority
- US 202062957999 P 20200107
- US 2021012553 W 20210107
Abstract (en)
[origin: WO2021142163A1] The present invention provides compositions and methods using certain GPR4-regulated genes and expression products thereof (namely YAP1, CTGF, CCND3, BDNF, VCL, ITGB3) for diagnosis, treatment and prevention of Alzheimer's disease and Mild Cognitive Impairment. The present invention also relates to a method of identifying therapeutic agents to treat and diagnose Alzheimer's disease or Mild Cognitive Impairment based on the differential expression of GPR4-regulated genes.
IPC 8 full level
A61P 25/28 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6883 (2018.01); G01N 33/50 (2006.01)
CPC (source: EP US)
A61P 25/28 (2018.01 - EP); C12Q 1/6883 (2013.01 - EP US); G01N 33/6896 (2013.01 - EP); C12Q 2600/106 (2013.01 - EP US); C12Q 2600/118 (2013.01 - US); C12Q 2600/136 (2013.01 - US); C12Q 2600/156 (2013.01 - EP); C12Q 2600/158 (2013.01 - US); G01N 2800/2814 (2013.01 - EP); G01N 2800/2821 (2013.01 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2021142163 A1 20210715; CN 114938633 A 20220823; EP 4087654 A1 20221116; EP 4087654 A4 20240306; JP 2023510297 A 20230313; US 2023348978 A1 20231102
DOCDB simple family (application)
US 2021012553 W 20210107; CN 202180008536 A 20210107; EP 21738088 A 20210107; JP 2022542062 A 20210107; US 202117791240 A 20210107