EP 4090932 A4 20231018 - SINGLE-SHEATH MICROFLUIDIC CHIP
Title (en)
SINGLE-SHEATH MICROFLUIDIC CHIP
Title (de)
EINSCHICHTIGER MIKROFLUIDISCHER CHIP
Title (fr)
PUCE MICROFLUIDIQUE À GAINE UNIQUE
Publication
Application
Priority
US 2020013392 W 20200113
Abstract (en)
[origin: WO2021145854A1] Microfluidic devices and methods for focusing components in a fluid sample are described herein. The microfluidic devices feature a microfluidic chip having a micro-channel having a constricting portion that narrows in width, and a flow focusing region downstream of the micro-channel. The flow focusing region includes a positively sloping bottom surface that reduces a height of the flow focusing region and sidewalls that taper to reduce a width of the flow focusing region, thereby geometrically constricting the flow focusing region. The devices and methods can be utilized in sex-sorting of sperm cells to improve performance and increase eligibility.
IPC 8 full level
G01N 1/20 (2006.01); A61D 19/02 (2006.01); A61K 35/52 (2015.01); B01L 3/00 (2006.01); C12M 1/00 (2006.01); C12M 3/00 (2006.01); C12N 5/00 (2006.01); G01N 15/00 (2006.01); G01N 15/06 (2006.01); G01N 15/10 (2006.01); G01N 15/14 (2006.01); G01N 21/64 (2006.01)
CPC (source: EP)
B01L 3/502761 (2013.01); B01L 3/502776 (2013.01); C12N 5/0081 (2013.01); G01N 15/06 (2013.01); G01N 15/1404 (2013.01); G01N 15/1459 (2013.01); G01N 15/1484 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0816 (2013.01); C12M 21/06 (2013.01); C12M 47/04 (2013.01); G01N 15/01 (2024.01); G01N 15/075 (2024.01); G01N 15/149 (2024.01); G01N 2015/1006 (2013.01); G01N 2015/1413 (2013.01); G01N 2015/1493 (2013.01); G01N 2015/1497 (2013.01)
Citation (search report)
- [X] US 2019187044 A1 20190620 - APPLEYARD DAVID [US], et al
- See references of WO 2021145854A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2021145854 A1 20210722; BR 112022012881 A2 20220906; CN 115023599 A 20220906; EP 4090932 A1 20221123; EP 4090932 A4 20231018; JP 2023514941 A 20230412
DOCDB simple family (application)
US 2020013392 W 20200113; BR 112022012881 A 20200113; CN 202080091173 A 20200113; EP 20913158 A 20200113; JP 2022540313 A 20200113