EP 4097166 C0 20240403 - MICELLAR COMPOSITION FROM AN AMPHIPHILIC COPOLYMER FOR TUMOR THERAPY
Title (en)
MICELLAR COMPOSITION FROM AN AMPHIPHILIC COPOLYMER FOR TUMOR THERAPY
Title (de)
MIZELLARE ZUSAMMENSETZUNG AUS EINEM AMPHIPHILEN COPOLYMER ZUR TUMORTHERAPIE
Title (fr)
COMPOSITION MICELLAIRE À PARTIR D'UN COPOLYMÈRE AMPHIPHILE POUR LE TRAITEMENT DE TUMEURS
Publication
Application
Priority
- EP 20154944 A 20200131
- EP 2021052303 W 20210201
Abstract (en)
[origin: WO2021152171A1] The invention relates to an amphiphilic copolymer comprising a first block, a second block and a linker covalently linking the first block with the second block, wherein the first block is a hydrophilic dendritic polyglycerol derivative having a polyglycerol backbone and carrying a plurality of sulfate or sulfonate residues substituting hydroxyl groups of the polyglycerol backbone, wherein the second block is a hydrophobic block comprising a polymer chosen from the group consisting of polycaprolactone, a polylactic acid polymer, and a copolymer of lactic acid and glycolic acid. The linker comprises a hydrocarbon having at least six consecutive methylene residues and a cleavable entity. The linker is devoid of a triazole-containing residue resulting from a reaction between an alkyne and an azide.
IPC 8 full level
C08G 63/08 (2006.01); C08G 63/685 (2006.01); C08G 63/688 (2006.01); C08G 65/34 (2006.01); C08G 65/48 (2006.01); C08G 81/00 (2006.01); C08G 83/00 (2006.01); C08L 71/08 (2006.01)
CPC (source: EP IL US)
A61K 9/1075 (2013.01 - IL US); A61K 47/34 (2013.01 - IL US); C08F 293/00 (2013.01 - IL US); C08G 63/08 (2013.01 - EP IL); C08G 63/6852 (2013.01 - EP IL); C08G 63/6882 (2013.01 - EP IL); C08G 65/34 (2013.01 - EP IL); C08G 65/48 (2013.01 - EP IL); C08G 81/00 (2013.01 - EP IL); C08G 83/006 (2013.01 - EP IL); C08L 67/04 (2013.01 - IL); C08L 71/08 (2013.01 - EP IL); C08G 2650/54 (2013.01 - EP IL)
C-Set (source: EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Participating member state (EPC – UP)
AT BE BG DE DK EE FI FR IT LT LU LV MT NL PT SE SI
DOCDB simple family (publication)
WO 2021152171 A1 20210805; CA 3168448 A1 20210805; EP 4097166 A1 20221207; EP 4097166 B1 20240403; EP 4097166 C0 20240403; IL 294845 A 20220901; IL 294845 B1 20231201; IL 294845 B2 20240401; US 2023080135 A1 20230316
DOCDB simple family (application)
EP 2021052303 W 20210201; CA 3168448 A 20210201; EP 21703860 A 20210201; IL 29484522 A 20220718; US 202117796672 A 20210201