EP 4100124 A1 20221214 - HETEROCYCLIC COMPOUNDS AS DIHYDROOROTATE DEHYDROGENASE INHIBITORS
Title (en)
HETEROCYCLIC COMPOUNDS AS DIHYDROOROTATE DEHYDROGENASE INHIBITORS
Title (de)
HETEROCYCLISCHE VERBINDUNGEN ALS DIHYDROOROTATDEHYDROGENASE-INHIBITOREN
Title (fr)
COMPOSÉS HÉTÉROCYCLIQUES UTILISÉS EN TANT QU'INHIBITEURS DE LA DIHYDROOROTATE DÉSHYDROGÉNASE
Publication
Application
Priority
- US 202062969688 P 20200204
- IB 2021050908 W 20210204
Abstract (en)
[origin: WO2021156787A1] Disclosed are compounds, compositions and methods for treating diseases, disorders, or medical conditions that are affected by the modulation of DHODH. Embodiments of such compounds are represented by Formula (I) and Formula (II) as follows: and wherein R1, R2, R3, R4, R5, R6, R7, R8, X1, X2, X3, X4, Y and Z, are defined herein.
IPC 8 full level
A61P 29/00 (2006.01); A61K 31/4709 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); C07D 215/38 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP KR)
A61K 31/437 (2013.01 - KR); A61K 31/4725 (2013.01 - KR); A61K 31/502 (2013.01 - KR); A61K 31/517 (2013.01 - KR); A61P 29/00 (2017.12 - EP KR); A61P 35/00 (2017.12 - EP KR); A61P 37/00 (2017.12 - EP KR); C07D 215/38 (2013.01 - EP); C07D 217/24 (2013.01 - KR); C07D 401/04 (2013.01 - EP KR); C07D 401/14 (2013.01 - EP KR); C07D 403/04 (2013.01 - EP KR); C07D 405/14 (2013.01 - EP KR); C07D 409/14 (2013.01 - EP KR); C07D 413/14 (2013.01 - EP KR); C07D 471/04 (2013.01 - EP KR)
Citation (search report)
See references of WO 2021156787A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2021156787 A1 20210812; AU 2021216714 A1 20220929; BR 112022015351 A2 20220920; CA 3170111 A1 20210812; CN 115427109 A 20221202; EP 4100124 A1 20221214; JP 2023513496 A 20230331; KR 20220137709 A 20221012; MX 2022009535 A 20221114
DOCDB simple family (application)
IB 2021050908 W 20210204; AU 2021216714 A 20210204; BR 112022015351 A 20210204; CA 3170111 A 20210204; CN 202180025845 A 20210204; EP 21704615 A 20210204; JP 2022547245 A 20210204; KR 20227030529 A 20210204; MX 2022009535 A 20210204