EP 4103168 A4 20240424 - PROCESS FOR THE PREPARATION OF GAMMA AMINO BUTYRIC ACIDS AND ANALOGS THEREOF
Title (en)
PROCESS FOR THE PREPARATION OF GAMMA AMINO BUTYRIC ACIDS AND ANALOGS THEREOF
Title (de)
VERFAHREN ZUR HERSTELLUNG VON GAMMA-AMINOBUTTERSÄUREN UND DEREN ANALOGEN
Title (fr)
PROCÉDÉ DE PRÉPARATION D'ACIDES GAMMA-AMINO-BUTYRIQUES ET DE LEURS ANALOGUES
Publication
Application
Priority
- IN 202011006475 A 20200214
- IN 2021050141 W 20210213
Abstract (en)
[origin: WO2021161346A1] The present invention relates to a process for the preparation of gamma aminobutyric acid derivatives of formula I, in particular pregabalin, baclofen and analogs thereof. Further, this process is comprised of preparation protocol for compounds of formula I, involving Michael addition and Beckmann rearrangement strategy.
IPC 8 full level
C07C 227/20 (2006.01); C07C 67/347 (2006.01); C07C 69/716 (2006.01); C07C 229/08 (2006.01); C07C 231/00 (2006.01); C07C 233/47 (2006.01); C07C 249/08 (2006.01); C07C 251/38 (2006.01)
CPC (source: EP)
C07C 67/347 (2013.01); C07C 227/20 (2013.01); C07C 231/00 (2013.01); C07C 249/08 (2013.01)
C-Set (source: EP)
Citation (search report)
[AD] H. ISHITANI, ET AL.: "Synthesis of (+/- )-pregabalin by utilising a three-step sequential-flow system with heterogeneous catalysts", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, vol. 2017, no. 44, 10 October 2017 (2017-10-10), Wiley-VCH Verlag, Weinheim, DE, pages 6491 - 6494, XP072119280, ISSN: 1434-193X, DOI: 10.1002/ejoc.201700998
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
WO 2021161346 A1 20210819; EP 4103168 A1 20221221; EP 4103168 A4 20240424; JP 2023513330 A 20230330; JP 7436689 B2 20240222
DOCDB simple family (application)
IN 2021050141 W 20210213; EP 21753915 A 20210213; JP 2022548730 A 20210213