Global Patent Index - EP 4103190 A4

EP 4103190 A4 20240703 - TREATMENT OF PATIENTS HAVING C-MET EXON 14 SKIPPING MUTATIONS

Title (en)

TREATMENT OF PATIENTS HAVING C-MET EXON 14 SKIPPING MUTATIONS

Title (de)

BEHANDLUNG VON PATIENTEN MIT C-MET-EXON-14-SKIPPING-MUTATIONEN

Title (fr)

TRAITEMENT DE PATIENTS AYANT DES MUTATIONS DE SAUT D'EXON 14 C-MET

Publication

EP 4103190 A4 20240703 (EN)

Application

EP 21754569 A 20210212

Priority

  • US 202062975406 P 20200212
  • IB 2021051203 W 20210212

Abstract (en)

[origin: US2021253717A1] The present invention relates to treatment of subjects having a cancer that is positive for c-Met exon 14 skipping mutations.

IPC 8 full level

A61K 31/53 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); C12Q 1/6886 (2018.01); G01N 33/574 (2006.01)

CPC (source: EP IL KR US)

A61K 31/53 (2013.01 - EP IL KR US); A61K 39/3955 (2013.01 - EP IL); A61K 45/06 (2013.01 - EP IL KR US); A61P 35/00 (2018.01 - EP IL KR US); C07K 16/2863 (2013.01 - EP IL KR US); C12Q 1/6886 (2013.01 - EP IL); G01N 33/57423 (2013.01 - EP IL); A61K 2039/505 (2013.01 - EP IL KR US); A61K 2039/507 (2013.01 - EP IL KR); A61K 2039/545 (2013.01 - EP IL KR US); A61K 2039/55 (2013.01 - EP IL KR); A61K 2300/00 (2013.01 - KR); C07K 2317/31 (2013.01 - EP IL KR US); C07K 2317/41 (2013.01 - EP IL); C07K 2317/73 (2013.01 - KR); C12Q 2600/106 (2013.01 - EP IL); C12Q 2600/156 (2013.01 - EP IL); G01N 2333/71 (2013.01 - EP IL); G01N 2333/82 (2013.01 - EP IL); G01N 2800/52 (2013.01 - EP IL)

C-Set (source: EP)

  1. A61K 31/53 + A61K 2300/00
  2. A61K 39/3955 + A61K 2300/00

Citation (search report)

  • [Y] US 2018057595 A1 20180301 - YANG YAN [US], et al
  • [Y] US 2014141000 A1 20140522 - CHIU MARK [US], et al
  • [XPI] WO 2020230091 A1 20201119 - JANSSEN BIOTECH INC [US]
  • [YP] US 2020270351 A1 20200827 - MOORES SHERI [US], et al
  • [Y] DATABASE ClinicalTrials.gov Archiv [online] ClinicalTrials.gov; 2 January 2020 (2020-01-02), ANONYMOUS: "Study of JNJ-61186372, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer", XP093162496, retrieved from https://classic.clinicaltrials.gov/ct2/history/NCT02609776?V_43=View#StudyPageTop Database accession no. NCT02609776
  • [A] JULIA K. ROTOW: "Co-occurring Alterations in the RAS-MAPK Pathway Limit Response to MET Inhibitor Treatment in MET Exon 14 Skipping Mutation-Positive Lung Cancer", CLINICAL CANCER RESEARCH, vol. 26, no. 2, 15 January 2020 (2020-01-15), US, pages 439 - 449, XP093162514, ISSN: 1078-0432, Retrieved from the Internet <URL:https://aacrjournals.org/clincancerres/article-pdf/26/2/439/2062155/439.pdf> [retrieved on 20240514], DOI: 10.1158/1078-0432.CCR-19-1667
  • [YP] DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; July 2020 (2020-07-01), DHILLON SOHITA: "Capmatinib: First Approval", XP002811559, Database accession no. PREV202000645361 & DRUGS, vol. 80, no. 11, July 2020 (2020-07-01), pages 1125 - 1131, ISSN: 0012-6667(print), DOI: 10.1007/S40265-020-01347-3
  • [AP] VIJAYARAGHAVAN SMRUTHI ET AL: "Amivantamab (JNJ-61186372), an Fc Enhanced EGFR/cMet Bispecific Antibody, Induces Receptor Downmodulation and Antitumor Activity by Monocyte/Macrophage Trogocytosis", MOLECULAR CANCER THERAPEUTICS, vol. 19, no. 10, 1 October 2020 (2020-10-01), US, pages 2044 - 2056, XP055922856, ISSN: 1535-7163, Retrieved from the Internet <URL:https://watermark.silverchair.com/2044.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAs8wggLLBgkqhkiG9w0BBwagggK8MIICuAIBADCCArEGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMaappgP0M8nEWTLwIAgEQgIICgs2yEP1pQc2P3mPmkhh4NN6ZpVCSGtqkmv0aZHIOIva3YYLWDzIFhk2IPPryjfU8GSgcvpiWqTjqfK4a2dXg4GPYa-WsQCy> [retrieved on 20240514], DOI: 10.1158/1535-7163.MCT-20-0071
  • See also references of WO 2021161262A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

Designated validation state (EPC)

KH MA MD TN

DOCDB simple family (publication)

US 2021253717 A1 20210819; AU 2021220009 A1 20221006; BR 112022015140 A2 20221011; CA 3170675 A1 20210819; CN 115087449 A 20220920; EP 4103190 A1 20221221; EP 4103190 A4 20240703; IL 295516 A 20221001; JO P20220184 A1 20230130; JP 2023513297 A 20230330; KR 20220140794 A 20221018; MX 2022009906 A 20221114; WO 2021161262 A1 20210819

DOCDB simple family (application)

US 202117174386 A 20210212; AU 2021220009 A 20210212; BR 112022015140 A 20210212; CA 3170675 A 20210212; CN 202180014425 A 20210212; EP 21754569 A 20210212; IB 2021051203 W 20210212; IL 29551622 A 20220810; JO P20220184 A 20210210; JP 2022548572 A 20210212; KR 20227031382 A 20210212; MX 2022009906 A 20210212