Global Patent Index - EP 4103746 A4

EP 4103746 A4 20240501 - METHODS AND SYSTEMS FOR NUCLEIC ACID AMPLIFICATION AND SEQUENCING

Title (en)

METHODS AND SYSTEMS FOR NUCLEIC ACID AMPLIFICATION AND SEQUENCING

Title (de)

VERFAHREN UND SYSTEME ZUR AMPLIFIKATION UND SEQUENZIERUNG VON NUKLEINSÄUREN

Title (fr)

MÉTHODES ET SYSTÈMES D'AMPLIFICATION ET DE SÉQUENÇAGE D'ACIDE NUCLÉIQUE

Publication

EP 4103746 A4 20240501 (EN)

Application

EP 21753841 A 20210212

Priority

  • US 202062976982 P 20200214
  • US 202062978744 P 20200219
  • US 202062987818 P 20200310
  • US 2021018032 W 20210212

Abstract (en)

[origin: WO2021163621A2] Disclosed herein are methods and systems for nucleic acid amplification, processing nucleic acid molecules, and sequencing nucleic acid molecule. The systems and methods described herein provide for blocking subsets of probes used for nucleic acid amplification and nucleic acid amplification at a subset of probes used for nucleic acid amplification. The systems and methods described herein provide for multiplexed sequencing of nucleic acid molecules. The systems and methods described herein thereby provide for sequencing one or more nucleic acid molecules substantially simultaneously. The systems and methods described herein provide for efficient incorporation of nucleotide bases. The systems and methods described herein thereby provide for sequencing one or more nucleic acid molecules with reduced dephasing.

IPC 8 full level

C12Q 1/6844 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/6837 (2018.01); C40B 40/06 (2006.01)

CPC (source: EP)

C12Q 1/6865 (2013.01)

C-Set (source: EP)

C12Q 1/6865 + C12Q 2565/543

Citation (search report)

[A] WO 2011025477 A1 20110303 - ILLUMINA INC [US], et al

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DOCDB simple family (publication)

WO 2021163621 A2 20210819; WO 2021163621 A3 20210923; EP 4103746 A2 20221221; EP 4103746 A4 20240501

DOCDB simple family (application)

US 2021018032 W 20210212; EP 21753841 A 20210212