EP 4114972 A1 20230111 - HIGH SEQUENCE FIDELITY NUCLEIC ACID SYNTHESIS AND ASSEMBLY
Title (en)
HIGH SEQUENCE FIDELITY NUCLEIC ACID SYNTHESIS AND ASSEMBLY
Title (de)
NUKLEINSÄURESYNTHESE UND -ANORDNUNG MIT HOHER SEQUENZTREUE
Title (fr)
SYNTHÈSE ET ASSEMBLAGE D'ACIDE NUCLÉIQUE À FIDÉLITÉ DE SÉQUENCE ÉLEVÉE
Publication
Application
Priority
- US 202062986209 P 20200306
- US 2021021104 W 20210305
Abstract (en)
[origin: WO2021178809A1] The present disclosure generally relates to compositions and methods for the synthesis of nucleic acid molecules with low error rates. Provided, as examples, are compositions and methods for high throughput synthesis and assembly of nucleic acid molecules, in many instances, with high sequence fidelity. In many instances, thermostable mismatch recognition proteins (e.g., thermostable mismatch binding protein, thermostable mismatch endonucleases) will be present in compositions and use methods provided.
IPC 8 full level
C12Q 1/686 (2018.01); C12N 15/10 (2006.01); C40B 50/00 (2006.01)
CPC (source: EP US)
C07H 21/00 (2013.01 - US); C12N 9/22 (2013.01 - US); C12N 15/1031 (2013.01 - EP); C12Q 1/686 (2013.01 - EP US); C40B 50/06 (2013.01 - EP)
C-Set (source: EP)
Citation (search report)
See references of WO 2021178809A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2021178809 A1 20210910; WO 2021178809 A9 20211007; CN 115244189 A 20221025; EP 4114972 A1 20230111; JP 2023516827 A 20230420; US 2024025939 A1 20240125
DOCDB simple family (application)
US 2021021104 W 20210305; CN 202180019185 A 20210305; EP 21714586 A 20210305; JP 2022578942 A 20210305; US 202117909091 A 20210305