EP 4121080 A1 20230125 - MOLECULAR TRANSPORT SYSTEM TO THE CENTRAL NERVOUS SYSTEM
Title (en)
MOLECULAR TRANSPORT SYSTEM TO THE CENTRAL NERVOUS SYSTEM
Title (de)
MOLEKULARES TRANSPORTSYSTEM ZUM ZENTRALNERVENSYSTEM
Title (fr)
SYSTÈME DE TRANSPORT MOLÉCULAIRE VERS LE SYSTÈME NERVEUX CENTRAL
Publication
Application
Priority
- US 202062991465 P 20200318
- US 2021022979 W 20210318
Abstract (en)
[origin: WO2021188802A1] Disclosed herein are MTS peptides or targeting peptides. Disclosed are MTS peptides comprising the amino acid sequence of any one of SEQ ID NOs: 1- 12. Disclosed are compositions comprising a peptide, wherein the peptide comprises a first MTS peptide conjugated to a cargo. Also disclosed are methods of using the MTS peptides. For example, disclosed are methods of transporting cargo to the CNS comprising administering one or more of the disclosed compositions to a subject in need thereof, wherein the peptide conjugated to cargo enters the CNS.
IPC 8 full level
A61K 38/00 (2006.01); A61K 47/64 (2006.01); A61K 47/65 (2006.01)
CPC (source: EP US)
A61K 47/64 (2017.08 - EP); A61P 25/00 (2018.01 - EP US); C07K 7/08 (2013.01 - EP US); A61K 38/00 (2013.01 - EP)
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2021188802 A1 20210923; AU 2021237644 A1 20221013; CN 115484970 A 20221216; EP 4121080 A1 20230125; JP 2023533407 A 20230803; US 2023174580 A1 20230608
DOCDB simple family (application)
US 2021022979 W 20210318; AU 2021237644 A 20210318; CN 202180028094 A 20210318; EP 21772024 A 20210318; JP 2022556681 A 20210318; US 202117912482 A 20210318