Global Patent Index - EP 4126813 A1

EP 4126813 A1 20230208 - PHENOLIC ACID LIPID BASED CATIONIC LIPIDS

Title (en)

PHENOLIC ACID LIPID BASED CATIONIC LIPIDS

Title (de)

KATIONISCHE LIPIDE AUF BASIS VON PHENOLSÄURELIPIDEN

Title (fr)

LIPIDES CATIONIQUES À BASE DE LIPIDE D'ACIDE PHÉNOLIQUE

Publication

EP 4126813 A1 20230208 (EN)

Application

EP 21720636 A 20210331

Priority

  • US 202063003698 P 20200401
  • US 2021025128 W 20210331

Abstract (en)

[origin: WO2021202694A1] The present invention provides, in part, phenolic acid lipid compounds of Formula (I), and sub-formulas thereof, or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.

IPC 8 full level

C07C 229/12 (2006.01); A61K 9/127 (2006.01); A61K 31/197 (2006.01); A61P 43/00 (2006.01); C07D 213/30 (2006.01); C07D 295/088 (2006.01); C12N 15/88 (2006.01)

CPC (source: EP)

A61K 9/1272 (2013.01); A61P 43/00 (2017.12); C07C 229/12 (2013.01); C07D 213/30 (2013.01); C07D 295/088 (2013.01); C12N 15/88 (2013.01)

Citation (search report)

See references of WO 2021202694A1

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

Designated validation state (EPC)

KH MA MD TN

DOCDB simple family (publication)

WO 2021202694 A1 20211007; CN 115667207 A 20230131; EP 4126813 A1 20230208; JP 2023520047 A 20230515

DOCDB simple family (application)

US 2021025128 W 20210331; CN 202180039080 A 20210331; EP 21720636 A 20210331; JP 2022559873 A 20210331