EP 4130253 A4 20240529 - T CELL PROGENITOR PRODUCTION METHOD
Title (en)
T CELL PROGENITOR PRODUCTION METHOD
Title (de)
VERFAHREN ZUR HERSTELLUNG VON T-ZELLVORLÄUFERN
Title (fr)
PROCÉDÉ DE PRODUCTION DE PROGÉNITEURS DES LYMPHOCYTES T
Publication
Application
Priority
- JP 2020062512 A 20200331
- JP 2021013465 W 20210330
Abstract (en)
[origin: EP4130253A1] The following are disclosed: a method for producing a T cell progenitor, including step (1) of culturing CD34<sup>+</sup> cell in a medium containing an aryl hydrocarbon receptor antagonist, a medium for T cell progenitor differentiation containing an aryl hydrocarbon receptor antagonist, and a T cell progenitor inducer containing an aryl hydrocarbon receptor antagonist.
IPC 8 full level
C12N 5/0783 (2010.01); A61K 35/17 (2015.01); A61P 37/04 (2006.01)
CPC (source: EP US)
A61K 39/4611 (2023.05 - EP US); A61K 39/464 (2023.05 - EP US); A61P 37/04 (2018.01 - EP); C12N 5/0636 (2013.01 - EP US); C12N 5/0647 (2013.01 - EP); C12N 2500/02 (2013.01 - EP US); C12N 2500/25 (2013.01 - EP); C12N 2501/115 (2013.01 - EP US); C12N 2501/125 (2013.01 - EP); C12N 2501/145 (2013.01 - EP); C12N 2501/155 (2013.01 - EP US); C12N 2501/165 (2013.01 - EP US); C12N 2501/2303 (2013.01 - EP US); C12N 2501/2306 (2013.01 - EP US); C12N 2501/2307 (2013.01 - EP US); C12N 2501/26 (2013.01 - EP); C12N 2501/42 (2013.01 - EP); C12N 2501/60 (2013.01 - EP); C12N 2501/727 (2013.01 - EP); C12N 2506/45 (2013.01 - EP US); C12N 2533/52 (2013.01 - EP)
Citation (search report)
- [X] WO 2013086436 A1 20130613 - HUTCHINSON FRED CANCER RES [US], et al
- [X] WO 2019067811 A1 20190404 - UNIV MINNESOTA [US], et al
- [X] STEFANSKI HEATHER ET AL: "Robust Progenitor T-cell Production From human Hematopoietic Progenitor Cell Expanded with Stemregenin-1", BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, vol. 24, 1 March 2018 (2018-03-01), US, pages S358 - S359, XP093149237, ISSN: 1083-8791, DOI: 10.1016/j.bbmt.2017.12.432
- [X] JACKSON CARLO STEPHAN ET AL: "Targeting the aryl hydrocarbon receptor nuclear translocator complex with DMOG and Stemregenin 1 improves primitive hematopoietic stem cell expansion", STEM CELL RESEARCH, vol. 21, 20 April 2017 (2017-04-20), pages 124 - 131, XP085038240, ISSN: 1873-5061, DOI: 10.1016/J.SCR.2017.04.007
- [A] BARI SUDIPTO ET AL: "Expansion and Homing of Umbilical Cord Blood Hematopoietic Stem and Progenitor Cells for Clinical Transplantation", BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, KLUGE CARDEN JENNINGS PUBLISHING, CHARLOTTESVILLE, VA, US, vol. 21, no. 6, 30 December 2014 (2014-12-30), pages 1008 - 1019, XP029155489, ISSN: 1083-8791, DOI: 10.1016/J.BBMT.2014.12.022
- See also references of WO 2021200901A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
DOCDB simple family (publication)
EP 4130253 A1 20230208; EP 4130253 A4 20240529; CN 115516084 A 20221223; JP WO2021200901 A1 20211007; TW 202204609 A 20220201; US 2023159891 A1 20230525; WO 2021200901 A1 20211007
DOCDB simple family (application)
EP 21779615 A 20210330; CN 202180026181 A 20210330; JP 2021013465 W 20210330; JP 2022512264 A 20210330; TW 110111630 A 20210330; US 202117915940 A 20210330