EP 4132473 A1 20230215 - PHARMACEUTICAL COMPOSITION FOR TREATING INFLAMMATORY BOWEL DISEASES
Title (en)
PHARMACEUTICAL COMPOSITION FOR TREATING INFLAMMATORY BOWEL DISEASES
Title (de)
PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR BEHANDLUNG VON ENTZÜNDLICHEN DARMERKRANKUNGEN
Title (fr)
COMPOSITION PHARMACEUTIQUE POUR LE TRAITEMENT DES MALADIES INFLAMMATOIRES INTESTINALES
Publication
Application
Priority
- FR 2003496 A 20200408
- EP 2021059076 W 20210407
Abstract (en)
[origin: WO2021204883A1] The invention relates to a pharmaceutical composition suitable for oral administration, containing as active ingredient a compound chosen from the group consisting of vorapaxar, vorapaxar isomers, atopaxar and 3,2-(chlorophenyl)-1-[4-(4-fluorobenzyl)piperazin-1-yl]propenone, and pharmaceutically acceptable salts thereof. This composition contains particles comprising a core containing a mixture of the active ingredient and of a substance capable of inhibiting recrystallisation of the active ingredient at a pH which has become greater than or equal to 5; and a pH-dependent, controlled-release coating layer covering said core, said coating layer being formed of a gastro-resistant coating agent and being porous.
IPC 8 full level
A61K 9/16 (2006.01); A61K 31/443 (2006.01); A61P 1/00 (2006.01)
CPC (source: EP)
A61K 9/1635 (2013.01); A61K 9/1652 (2013.01); A61K 31/443 (2013.01); A61P 1/00 (2017.12)
Citation (search report)
See references of WO 2021204883A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
WO 2021204883 A1 20211014; EP 4132473 A1 20230215; FR 3109089 A1 20211015; FR 3109089 B1 20230414
DOCDB simple family (application)
EP 2021059076 W 20210407; EP 21715934 A 20210407; FR 2003496 A 20200408