EP 4135714 A1 20230222 - PHOSPHOLIPIDS AND PHOSPHOLIPID METABOLITES FOR TREATING VIRAL AND BACTERIAL PNEUMONIA AND SEPSIS
Title (en)
PHOSPHOLIPIDS AND PHOSPHOLIPID METABOLITES FOR TREATING VIRAL AND BACTERIAL PNEUMONIA AND SEPSIS
Title (de)
PHOSPHOLIPIDE UND PHOSPHOLIPID-METABOLITEN ZUR BEHANDLUNG VON VIRALEN UND BAKTERIELLEN LUNGENENTZÜNDUNGEN UND SEPSIS
Title (fr)
PHOSPHOLIPIDES ET MÉTABOLITES DE PHOSPHOLIPIDES DESTINÉS AU TRAITEMENT DE LA PNEUMONIE VIRALE ET BACTÉRIENNE ET DE LA SEPTICÉMIE
Publication
Application
Priority
- EP 20170199 A 20200417
- EP 2021059881 W 20210416
Abstract (en)
[origin: WO2021209589A1] The invention relates to lysophosphatidylcholine (LysoPC), or a suitable precursor or derivative thereof, or a composition containing LysoPC and/or one or more suitable precursors or derivatives thereof, for use in the treatment and aftertreatment of human inflammatory diseases associated with a decrease in LysoPC levels, including the treatment, prevention, or treatment support and aftertreatment support of viral and bacterial pneumonia and sepsis, including pneumonia and sepsis as a result of influenza, Covid-19, ARDS, cancer, to support the efficacy of immunotherapy for cancer and to reduce side effects such as pneumonitis, colitis or hepatitis, and to reduce vaccine reactions. The invention also relates to alpha-glycerophosphocholine (alpha-GPC) or a variant thereof, or a composition comprising alpha-GPC and/or one or more variants thereof, for use in the treatment and aftertreatment of cancer and tumour cachexia.
IPC 8 full level
A61K 31/685 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01)
CPC (source: EP US)
A61K 9/0053 (2013.01 - US); A61K 31/685 (2013.01 - EP US); A61K 45/06 (2013.01 - US); A61P 29/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/02 (2017.12 - EP); Y02A 50/30 (2017.12 - EP)
Citation (search report)
See references of WO 2021209589A1
Designated contracting state (EPC)
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated extension state (EPC)
BA ME
Designated validation state (EPC)
KH MA MD TN
DOCDB simple family (publication)
EP 3895709 A1 20211020; EP 4135714 A1 20230222; US 2023226087 A1 20230720; WO 2021209589 A1 20211021
DOCDB simple family (application)
EP 20170199 A 20200417; EP 2021059881 W 20210416; EP 21718135 A 20210416; US 202117996370 A 20210416