Global Patent Index - EP 4148120 A1

EP 4148120 A1 20230315 - RECOMBINANT STRAIN PRODUCING L-LYSINE AND CONSTRUCTION METHODS THEREFOR AND USE THEREOF

Title (en)

RECOMBINANT STRAIN PRODUCING L-LYSINE AND CONSTRUCTION METHODS THEREFOR AND USE THEREOF

Title (de)

REKOMBINANTER L-LYSIN PRODUZIERENDER STAMM UND KONSTRUKTIONSVERFAHREN DAFÜR UND VERWENDUNG DAVON

Title (fr)

SOUCHE RECOMBINÉE PRODUISANT DE LA L-LYSINE, PROCÉDÉS DE CONSTRUCTION CORRESPONDANTS ET LEUR UTILISATION

Publication

EP 4148120 A1 20230315 (EN)

Application

EP 20939893 A 20201230

Priority

  • CN 202010514023 A 20200608
  • CN 202010790877 A 20200807
  • CN 2020141539 W 20201230

Abstract (en)

Provided are a method for introducing point mutations to the coding sequence of NCg12176 gene or improving the expression thereof in Corynebacterium glutamicum, and a method for performing point mutations on the promoter region sequence of dapB gene in Corynebacterium glutamicum. The fermentation yield of L-lysine produced by a strain with the mutations can be increased by means of the methods.

IPC 8 full level

C12N 1/21 (2006.01); C07K 14/34 (2006.01); C12N 15/10 (2006.01); C12N 15/113 (2010.01); C12N 15/31 (2006.01); C12N 15/53 (2006.01); C12N 15/77 (2006.01); C12P 13/08 (2006.01)

CPC (source: EP KR US)

C07K 14/34 (2013.01 - EP KR US); C12N 1/00 (2013.01 - US); C12N 9/0004 (2013.01 - US); C12N 9/001 (2013.01 - EP); C12N 9/0093 (2013.01 - EP); C12N 15/102 (2013.01 - KR); C12N 15/77 (2013.01 - EP KR US); C12N 15/902 (2013.01 - KR); C12P 13/08 (2013.01 - EP KR US); C12R 2001/15 (2021.05 - EP)

Designated contracting state (EPC)

AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Designated extension state (EPC)

BA ME

Designated validation state (EPC)

KH MA MD TN

DOCDB simple family (publication)

EP 4148120 A1 20230315; EP 4148120 A4 20241002; BR 112022017298 A2 20230207; JP 2023527951 A 20230703; KR 20230002331 A 20230105; MX 2022013618 A 20221116; US 2023295645 A1 20230921; WO 2021248890 A1 20211216

DOCDB simple family (application)

EP 20939893 A 20201230; BR 112022017298 A 20201230; CN 2020141539 W 20201230; JP 2022552166 A 20201230; KR 20227032897 A 20201230; MX 2022013618 A 20201230; US 202018001070 A 20201230